70328-76-6Relevant academic research and scientific papers
Gold-catalyzed oxidative acyloxylation of arenes
Pradal, Alexandre,Toullec, Patrick Y.,Michelet, Veronique
supporting information; experimental part, p. 6086 - 6089 (2011/12/22)
A variety of nonactivated hindered aromatic rings are acyloxylated (22 examples, up to 83% yield) in the presence of PPh3AuCl as the catalyst and di(acetoxy)iodobenzene as the oxidant. The reaction proceeds at 110 °C in an acid media and allows the formation of both hindered acetoxy and acyloxy derivatives. This methodology nicely complements the Pd-catalyzed arene acyloxylation reaction, which is not operating on hindered substrates and allows the Au-catalyzed unprecedented acyloxylation reaction of arenes, implying various carboxylic acids.
Studies on Electrolytic Substitution Reactions. XVII. Selective Nuclear Acetoxylation of Alkylaromatic Compounds
Eberson, Lennart,Oberrauch, Ermanno
, p. 193 - 196 (2007/10/02)
Anodic nuclear monoacetoxylation of alkylaromatics (p-xylene, isodurene, mesitylene, durene) can be achieved with high selectivity with respect to the side-chain acetate by carrying out the electrolysis in the presence of Pd on carbon in a nondevided cell.This arrangement utilizes cathodically generated hydrogen to effect cleavage of the benzylic acetate as it is formed, thus continuously regenerating the substrate.The nuclear acetate which is resistant toward hydrogenolysis accumulates in the reaction moxture.
