70340-02-2

Upstream product

• 98-88-4 benzoyl chloride 
• 95-48-7 ortho-cresol 
• 80645-54-1 acetate de benzoyl-4 bromomethyl-2 phenyle 
• 80645-49-4 acetate de benzoyl-4 methyl-2 phenyle 
• 5326-42-1 3-methyl-4-hydroxybenzophenone 
• 617-02-7 2-methylphenyl benzoate 
• 80645-58-5 bromure de acetoxy-2 benzoyl-5 benzyltriphenylphosphonium 

Relevant academic research and scientific papers

Process for the synthesis of derivatives of the benzofuran, chromene and isochromene type

The invention relates to a process for the production of therapeutic compounds of the benzofuran, chromene and isochromene type of the general formula; STR1 in which formula, STR2 R1 and R3 =H, lower alkyl, aralkyl or cycloalkyl R2 =H or an organic radical and when D= STR3 R1 and R3 may represent an organic radical. The process comprising the cyclization in the liquid phase and in the presence of a base a compound of the formula; STR4 in which formula; R'=an alkyl, aryl or aralkyl radical and X- =an anion.