70361-43-2

Upstream product

• 55685-98-8 4-isopropyl-4-(2-nitro-benzyl)-2-phenyl-4H-oxazol-5-one 
• 563-80-4 3-methyl-butan-2-one 
• 577-19-5 2-nitrophenyl bromide 
• 914920-08-4 2-(2-nitro-phenyl)-3-oxy-4-methyl-pentanoic acid methyl ester 
• 612-23-7 2-nitrobenzyl chloride 

Downstream Products

• 17790-93-1 2-isopropyl-1H-indole 

Relevant academic research and scientific papers

Process for the preparation of a carboxamide derivative

Process for the preparation of a carboxamide derivative of general formula (I) or a salt thereof Intermediates for preparing this compound.

An annulative approach to highly substituted indoles: Unusual effect of phenolic additives on the success of the arylation of ketone enolates

A novel palladium-catalyzed arylation of ketone enolates with o-nitrohaloarenes was achieved through the addition of phenol additives. The mild reaction conditions employed allowed for the inclusion of a wide variety of functional groups in both substrates to be tolerated. The products of this reaction were then readily reductively cyclized to give highly substituted indoles in moderate to excellent overall yields. Copyright