70379-70-3Relevant academic research and scientific papers
Studies of Pyrimidine Derivatives. XVII. Synthesis of 2- and 4-Pyrimidinyl Ketones by Means of the Hydration Alkynylpyrimidines
Tanji, Ken-Ichi,Sakamoto, Takao,Yamanaka, Hiroshi
, p. 1865 - 1867 (2007/10/02)
In the palladium-catalyzed cross-coupling reaction of halopyrimidines with terminal acetylenes, 2 and 4-chloropyrimidines can be used as starting compounds, though their reactivity is inferior to that of 2 and 4-iodopyrimidines.The conversion of the 2 and
Studies on Pyrimidine Derivatives. XXIV. Synthesis of 3-Substituted 1,2,4-Triazines by Nucleophilic Substitution
Konno, Shoetsu,Yokoyama, Masaaki,Kaite, Akiko,Yamatsuta, Ikuko,Ogawa, Shigeru,et. al.
, p. 152 - 157 (2007/10/02)
The potassium permanganate oxidation of 3-methylthio-5,6-diphenyl-as-triazine in the presence of a phase-transfer catalyst afforded 3-methylsulfonyl-5,6-diphenyl-as-triazine.The 3-sulfonyl-as-triazine readily reacted not only with active methylene compounds but also with methyl or methylene ketones under basic conditions, and 5,6-diphenyl-as-triazines containing a functionalized carbon substituent at the 3-position were obtained.Similarly, 2-substituted 4,6-dimethylpyrimidines were synthesized by the nucleophilic substitution of 4,6-dimethyl-2-phenylsulfonylpyrimidine with various ketones.
Studies on Pyrimidine Derivatives. XXIII. Synthesis of Acylmethylpyrimidines and Related Compounds via Imidoyl-substituted Oxosulfonium Ylides
Yamanaka, Hiroshi,Konno, Shoetsu,Sakamoto, Takao,Niitsuma, Setsuko,Noji, Sayo
, p. 2837 - 2843 (2007/10/02)
The reaction of 2- and 4-chloropyrimidines with dimethyloxosulfonium methylide afforded the corresponding pyrimidinylmethylides.Pyrimidine derivatives containing a functionalized side chain such as acetonyl, phenacyl, ethoxycarbonyl, or N-phenylcarbamoyl
