70388-36-2Relevant academic research and scientific papers
Tandem carbonyl ene cyclization-cycloalkylation: A route to trifluoromethyl diterpenoids
Abouabdellah, Ahmed,Bonnet-Delpon, Daniele
, p. 11921 - 11932 (2007/10/02)
A new sequential carbonyl-ene cyclization/cycloalkylation of trifluoromethyl ketones catalyzed by aluminum Lewis acids is described. From ketone 1, the 4-CF3-4-OH cis-octahydrophenanthrene 6 is obtained in 50% yield. From ketone 2, with MeAlCl
