704-84-7Relevant academic research and scientific papers
Synthesis of α-Amidoketones from Vinyl Esters via a Catalytic/Thermal Cascade Reaction
Holthusen, Katharina,Leitner, Walter,Franciò, Giancarlo
, p. 4823 - 4828 (2016/07/06)
A straightforward, modular, and atom-efficient method is reported for the synthesis of α-amidoketones from vinyl esters via a cascade reaction including hydroformylation, condensation with a primary amine, and a rearrangement step giving water as the only byproduct. The reaction sequence can be performed in one pot or as a three-step procedure. The synthetic applicability is demonstrated by the preparation of different α-amidoketones in moderate to good yields.
Ethenolate transfer reactions: A facile synthesis of vinyl esters
Appaye, Srinivasan Kaliyaperumal,Nikumbh, Satish Pandurang,Govindapur, Rajeshwar Reddy,Banerjee, Shyamapada,Bhalerao, Dinesh S.,Kumar, Unniaran K. Syam
, p. 1115 - 1122 (2014/09/17)
A simple and efficient metal-free ethenolate transfer reaction has been elaborated in moderate-to-high yields from vinyl acetate. This reaction was accomplished by generation of potassium ethenolate, which was then reacted with homo and mixed anhydrides of aliphatic, aryl and heteroaryl acids, to yield the corresponding vinyl esters. The utility of thus generated vinyl esters was then probed by carrying out intramolecular Heck reactions to give isobenzofuran-1(3H)-one derivatives in excellent yields. Copyright
An expedient biocatalytic procedure for abasic site precursors useful in oligonucleotide synthesis
Martinez-Montero, Saul,Fernandez, Susana,Sanghvi, Yogesh S.,Gotor, Vicente,Ferrero, Miguel
experimental part, p. 5960 - 5966 (2011/10/05)
Preparation of abasic site precursors through a divergent chemoenzymatic synthesis has been accomplished. Several biocatalysts and acylating agents were studied furnishing a practical and scalable green method useful for industrial applications. Highly re
