70403-11-1 Usage
Structure
Piperazine derivative with two benzyl groups and an acetonitrile group attached
Potential applications
Medicinal chemistry, drug development, building block for synthesis of other organic compounds, starting material for new drugs or therapeutic agents
Chemical and physical properties
Not extensively studied, but likely to exhibit characteristics common to similar piperazine derivatives such as solubility in organic solvents and compatibility with various reaction conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 70403-11-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,4,0 and 3 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 70403-11:
(7*7)+(6*0)+(5*4)+(4*0)+(3*3)+(2*1)+(1*1)=81
81 % 10 = 1
So 70403-11-1 is a valid CAS Registry Number.
70403-11-1Relevant articles and documents
KRAS MUTANT PROTEIN INHIBITORS
-
Paragraph 0199, (2021/04/02)
The invention relates to a KRAS mutant protein inhibitor, a composition containing the inhibitor and the use thereof.
SPIROCYCLIC TETRAHYDROQUINAZOLINES
-
Paragraph 0499; 0501-0502, (2021/07/17)
Provided are compounds represented by Formula I, wherein R3, A, A1, A2, A3, E, E1, E2, L, Q, Z, and (aa) are as defined in the specification, and the pharmaceutically acceptable salts and solvates thereof. Compounds of Formula (I) are KRAS inhibitors and are thus useful to treat cancer and other diseases.
KRAS G12C INHIBITORS
-
Paragraph 0295; 0296, (2020/07/25)
The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
