70458-97-8 Usage
Type of chemical
Quinolone antibiotic
Function
Treats various bacterial infections
Mechanism of action
Inhibits the synthesis of bacterial DNA
Effectiveness
Against a wide range of bacteria, including gram-positive and gram-negative strains
Usage
Often used in combination with other antibiotics for broader spectrum of activity
Forms available
Oral tablets and intravenous injections
Administration
Suitable for different administration routes
Supervision
Should be strictly supervised by a healthcare professional
Purpose
To ensure proper dosage and minimize the risk of antibiotic resistance
Check Digit Verification of cas no
The CAS Registry Mumber 70458-97-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,4,5 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 70458-97:
(7*7)+(6*0)+(5*4)+(4*5)+(3*8)+(2*9)+(1*7)=138
138 % 10 = 8
So 70458-97-8 is a valid CAS Registry Number.
70458-97-8Relevant academic research and scientific papers
Structure-Activity Relationships of Antibacterial 6,7- and 7,8-Disubstituted 1-Alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic Acids
Koga, Hiroshi,Itoh, Akira,Murayama, Satoshi,Suzue, Seigo,Irikura, Tsutomu
, p. 1358 - 1363 (2007/10/02)
Previous quantitative and qualitative structure-activity studies in antibacterial monosubstituted 1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids prompted us to synthesize the 6,7,8-polysubstituted compounds.In this paper, the preparation and antibacterial activity of the 6,7- and 7,8-disubstituted compounds and their derivatives are described.Among these compounds, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinoline-3-carboxylic acid (34) possessed many significant activities and was more active than oxolinic acid (84) against Gram-positive andGram-negative bacteria.Structure activity relationships are discussed.
