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3,5-Dichlorobenzenesulfonyl chloride is an organic compound with the chemical formula C6H3Cl3SO2Cl. It is a derivative of benzene, featuring two chlorine atoms at the 3rd and 5th positions, a sulfonyl group (-SO2-), and a chlorine atom attached to the sulfonyl group. 3,5-Dichlorobenzenesulfonyl chloride is a white to pale yellow crystalline solid and is soluble in organic solvents. It is primarily used as a reagent in organic synthesis, particularly in the preparation of sulfonamides and other sulfur-containing compounds. Due to its reactivity and potential hazards, it is important to handle 3,5-dichlorobenzenesulfonyl chloride with care, following proper safety protocols.

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  • 705-21-5 Structure
  • Basic information

    1. Product Name: 3,5-Dichlorobenzenesulfonyl chloride
    2. Synonyms: BUTTPARK 95\57-48;3,5-DICHLOROBENZENESULFONYL CHLORIDE;3,5-DICHLOROBENZENE-1-SULFONYL CHLORIDE;3,5-DICHLOROBENZENESULPHONYL CHLORIDE;3,5-Dichlorobenzenesulfonyl chloride,98%;3,5-Dichlorobenzene-1-sulfonyl chloride, 95%+;3,5-Dichlorobenzenesulfonyl chloride, 98% 1GR;3,5-Dichlorobenzenesulfonyl chloride, 98% 5GR
    3. CAS NO:705-21-5
    4. Molecular Formula: C6H3Cl3O2S
    5. Molecular Weight: 245.51
    6. EINECS: -0
    7. Product Categories: Fluorobenzene;Benzenesulfonyl chloride;Benzene derivates;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
    8. Mol File: 705-21-5.mol
  • Chemical Properties

    1. Melting Point: 32-35 °C(lit.)
    2. Boiling Point: 83-84°C 0,1mm
    3. Flash Point: >230 °F
    4. Appearance: beige low melting solid
    5. Density: 1.363 g/cm3
    6. Vapor Pressure: 0.000249mmHg at 25°C
    7. Refractive Index: 1.581
    8. Storage Temp.: Inert atmosphere,Room Temperature
    9. Solubility: soluble in Toluene
    10. Sensitive: Moisture Sensitive
    11. BRN: 1528657
    12. CAS DataBase Reference: 3,5-Dichlorobenzenesulfonyl chloride(CAS DataBase Reference)
    13. NIST Chemistry Reference: 3,5-Dichlorobenzenesulfonyl chloride(705-21-5)
    14. EPA Substance Registry System: 3,5-Dichlorobenzenesulfonyl chloride(705-21-5)
  • Safety Data

    1. Hazard Codes: C
    2. Statements: 34
    3. Safety Statements: 26-36/37/39-45
    4. RIDADR: UN 1759 8/PG 2
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: 8
    8. PackingGroup: II
    9. Hazardous Substances Data: 705-21-5(Hazardous Substances Data)

705-21-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 705-21-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 705-21:
(5*7)+(4*0)+(3*5)+(2*2)+(1*1)=55
55 % 10 = 5
So 705-21-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H3Cl3O2S/c7-4-1-5(8)3-6(2-4)12(9,10)11/h1-3H

705-21-5 Well-known Company Product Price

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  • Alfa Aesar

  • (A11003)  3,5-Dichlorobenzenesulfonyl chloride, 97%   

  • 705-21-5

  • 1g

  • 423.0CNY

  • Detail
  • Alfa Aesar

  • (A11003)  3,5-Dichlorobenzenesulfonyl chloride, 97%   

  • 705-21-5

  • 5g

  • 842.0CNY

  • Detail
  • Alfa Aesar

  • (A11003)  3,5-Dichlorobenzenesulfonyl chloride, 97%   

  • 705-21-5

  • 25g

  • 3582.0CNY

  • Detail
  • Aldrich

  • (546933)  3,5-Dichlorobenzenesulfonylchloride  97%

  • 705-21-5

  • 546933-5G

  • 1,027.26CNY

  • Detail
  • Aldrich

  • (546933)  3,5-Dichlorobenzenesulfonylchloride  97%

  • 705-21-5

  • 546933-25G

  • 3,769.74CNY

  • Detail

705-21-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,5-Dichlorobenzenesulfonyl Chloride

1.2 Other means of identification

Product number -
Other names 3,5-Dichlorobenzenesulfonyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:705-21-5 SDS

705-21-5Relevant articles and documents

Quinazolinone Compound and Application Thereof

-

Paragraph 0818-0820, (2020/11/27)

The present invention relates to a series of quinazolinone compounds and applications thereof as PI3Kα inhibitors. In particular, the present invention relates to a compound shown in formula (I) and a tautomer or pharmaceutically acceptable salt thereof.

A simple and highly effective oxidative chlorination protocol for the preparation of arenesulfonyl chlorides

Pu, Yu-Ming,Christesen, Alan,Ku, Yi-Yin

supporting information; experimental part, p. 418 - 421 (2010/03/04)

2,4-Dichloro-5,5-dimethylhydantoin (DCDMH) was found to be a mild and efficient reagent for the direct oxidative conversion of sulfur compounds to the corresponding arenesulfonyl chlorides in good to excellent yields through oxidative chlorination. The method is suitable for many types of sulfur substrates (thiols, disulfides, and benzylic sulfides). The overall process is simple, practical, and it provides convenient access to a variety of aryl or heteroarylsulfonyl chlorides. The mild reaction conditions and the broad substrate scope render this method attractive and complementary to existing syntheses of aryl or heteroarylsulfonyl chlorides.

Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists

-

, (2008/06/13)

The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.

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