70508-89-3Relevant academic research and scientific papers
Anti-inflammatory/antiarthritic ketonic bisphosphonic acid esters
Schlachter, Stephen T.,Galinet, Louise A.,Shields, Sharon K.,Aspar, Danielle G.,Dunn, Colin J.,Staite, Nigel D.,Nugent, Richard A.
, p. 1093 - 1096 (1998)
Bisphosphonate ester 2 is an inhibitor of inflammation, but is devoid of antiarthritic effects. SAR studies on a series of related bisphosphonate esters resulted in compounds 6e, 6i, 6j, and 6m, which exhibited excellent inhibition of an arthritis model, in addition to potent anti-inflammatory effects.
