705259-94-5Relevant academic research and scientific papers
O-Arylmandelic acids as highly selective human PPAR α/γ agonists
Adams, Alan D.,Hu, Zao,Von Langen, Derek,Dadiz, Adonis,Elbrecht, Alex,MacNaul, Karen L.,Berger, Joel P.,Zhou, Gaochao,Doebber, Thomas W.,Meurer, Roger,Forrest, Michael J.,Moller, David E.,Jones, A. Brian
, p. 3185 - 3190 (2007/10/03)
A new class of O-arylmandelic acid PPAR agonists show excellent anti-hyperglycemic efficacy in a db/db mouse model of DM2. These PPARα-weighted agonists do not show the typical PPARγ associated side effects of BAT proliferation and cardiac hypertrophy in
