355387-55-2

Basic information

• Product Name: 1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone
• Synonyms: 1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone
• CAS NO: 355387-55-2
• Molecular Weight: 290.282
• Mol File: 355387-55-2.mol

Chemical Properties

• CAS DataBase Reference: 1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone(355387-55-2)
• EPA Substance Registry System: 1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone(355387-55-2)

Safety Data

• Hazardous Substances Data: 355387-55-2(Hazardous Substances Data)

Upstream product

• 705257-43-8 4-allyl-2-propyl-benzene-1,3-diol 
• 705257-21-2 3-allyloxy-2-propyl-phenol 
• 13331-19-6 2-propyl-1,3-benzenediol 
• 108-46-3 recorcinol 
• 13594-95-1 1,3-bis(allyloxy)benzene 
• 71489-64-0 2,4-diallyl-1,3-benzenediol 
• 407-25-0 trifluoroacetic anhydride 
• 355387-54-1 2,4-di-n-propylbenzene-1,3-diol 

Downstream Products

• 705259-94-5 (S)-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-phenyl-acetic acid (S)-1-methyl-2-oxo-2-pyrrolidin-1-yl-ethyl ester 
• 449780-14-7 (5,7-dipropyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-[4-(pyridin-2-ylmethoxy)-phenyl]-acetic acid methyl ester 
• 449779-52-6 (5,7-dipropyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-(4-isopropyl-phenyl)-acetic acid methyl ester 
• 449779-50-4 (4-chloro-phenyl)-(5,7-dipropyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-acetic acid methyl ester 
• 449779-49-1 (5,7-dipropyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-phenyl-acetic acid methyl ester 
• 475271-37-5 (1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime 
• 355387-56-3 2,4-dihydroxy-3,5-dipropyl-1',1',1'-trifluoroacetophenone oxime 

Relevant articles and documents

Discovery of a novel series of peroxisome proliferator-activated receptor α/γ dual agonists for the treatment of type 2 diabetes and dyslipidemia

A series of 2-aryloxy-2-methyl-propionic acid compounds and related analogues were designed, synthesized, and evaluated for their PPAR agonist activities. 2-[(5,7-Dipropyl-3-trifluoromethyl)-benzisoxazol-6-yloxy]-2- methylpropionic acid (4) was identified

An efficient synthesis of a dual PPAR α/γ agonist and the formation of a sterically congested α-aryloxyisobutyric acid via a Bargellini reaction

A practical synthesis of benzisoxazole 1 and its conversion to α-aryloxyisobutyric acid 2 using 1,1,1-trichloro-2-methyl-2-propanol (chloretone) was developed. Benzisoxazole 1 was formed in high yields by the action of either methanesulfonyl chloride/base

O-Arylmandelic acids as highly selective human PPAR α/γ agonists

A new class of O-arylmandelic acid PPAR agonists show excellent anti-hyperglycemic efficacy in a db/db mouse model of DM2. These PPARα-weighted agonists do not show the typical PPARγ associated side effects of BAT proliferation and cardiac hypertrophy in