705299-64-5Relevant academic research and scientific papers
Highly anti-selective asymmetric aldol reactions using chiral zirconium catalysts. Improvement of activities, structure of the novel zirconium complexes, and effect of a small amount of water for the preparation of the catalysts
Yamashita, Yasuhiro,Ishitani, Haruro,Shimizu, Haruka,Kobayashi, Shu
, p. 3292 - 3302 (2002)
Catalytic asymmetric aldol reactions of silyl enol ethers with aldehydes (Mukaiyama aldol reactions) have been performed using novel chiral zirconium catalysts. The reactions proceeded in high yields under mild conditions, and anti-adducts were obtained i
Storable, powdered chiral zirconium complex for asymmetric aldol and hetero Diels-Alder reactions
Seki, Kazutaka,Ueno, Masaharu,Kobayashi, Shu
, p. 1347 - 1350 (2008/01/01)
A storable, powdered chiral zirconium catalyst for asymmetric aldol and hetero Diels-Alder reactions has been developed. The catalyst has the same activity as that prepared in situ even after being stored for 3 months. Moreover, this chiral Zr catalyst wo
An air-stable, storable chiral zirconium catalyst for asymmetric aldol reactions
Kobayashi, Shue,Saito, Susumu,Ueno, Masaharu,Yamashita, Yasuhiro
, p. 2016 - 2017 (2007/10/03)
Asymmetric aldol reactions of ketene silyl acetals with aldehydes using an air-stable, storable chiral zirconium catalyst, which could be stored for at least 13 weeks at room temperature, proceeded smoothly to afford the desired adducts in high yields wit
The catalytic asymmetric aldol reaction of aldehydes with unsubstituted and monosubstituted silyl ketene acetals: Formation of anti-β-hydroxy-α-methyl esters
Parmee,Hong,Tempkin,Masamune
, p. 1729 - 1732 (2007/10/02)
The title rection with unsubstituted and monosubstituted silyl ketene acetals proceeds with high enantioselectivity, and in the latter case good diastereoselectivity favoring the anti-β-hydroxy-α-methyl esters in all reported cases.
