70538-52-2 Usage
Uses
Used in Pharmaceutical Industry:
5-nitroisoquinoline-1-carbonitrile is used as a key intermediate for the development of drugs with antitumor, antibacterial, and antiviral properties. Its unique chemical structure allows for the creation of various therapeutic agents that can target different biological pathways and mechanisms.
Used in Organic Chemistry Reactions:
5-nitroisoquinoline-1-carbonitrile is employed as a reagent in various organic chemistry reactions, facilitating the synthesis of more complex molecules. Its presence in these reactions can enhance the yield and selectivity of the desired products.
Used in Agrochemical Production:
In the agrochemical industry, 5-nitroisoquinoline-1-carbonitrile is utilized as a starting material for the synthesis of pesticides and other crop protection agents. Its chemical properties enable the development of effective compounds that can protect crops from pests and diseases.
Used in Organic Synthesis:
5-nitroisoquinoline-1-carbonitrile is used as a versatile building block in the synthesis of a variety of organic compounds. Its presence in these syntheses can lead to the formation of new molecules with unique properties and potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 70538-52-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,5,3 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 70538-52:
(7*7)+(6*0)+(5*5)+(4*3)+(3*8)+(2*5)+(1*2)=122
122 % 10 = 2
So 70538-52-2 is a valid CAS Registry Number.
70538-52-2Relevant academic research and scientific papers
Regioselective Cyanation of Six-Membered N-Heteroaromatic Compounds Under Metal-, Activator-, Base- and Solvent-Free Conditions
Sarmah, Bikash Kumar,Konwar, Monuranjan,Bhattacharyya, Dipanjan,Adhikari, Priyanka,Das, Animesh
supporting information, p. 5616 - 5625 (2019/11/22)
A regioselective cyanation of heteroaromatic N-oxides with trimethylsilyl cyanide has been developed to obtain 2-substituted N-heteroaromatic nitrile without the requirement of any external activator-, metal-, base-, and solvent. The present protocol is a straightforward, one-pot heteroaromatic C?H cyanation process, and proceeds smoothly in conventional heating but also under microwave irradiation with shorter reaction times. This approach now allows access to a broad class of quinoline N-oxides and other heteroarene N-oxides with high to good yields and can also be scaled up to obtain gram quantities. Further application of this process was observed and utilized in late-stage cyanation of the anti-malarial drug quinine as well as transformation of the 2-cyanoazines to a series of biologically important molecules. Based on the experimental observations, a plausible mechanism has also been proposed highlighting the dual role of trimethylsilyl cyanide as a nitrile source and as an activating agent. (Figure presented.).
