7055-53-0

Usage

Uses

Used in Pharmaceutical Industry:
(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one is used as a pharmaceutical agent for its potential role in the regulation of mood and stress. Its physiological effects make it a promising candidate for the development of treatments for mood disorders and stress-related conditions.
Used in Research Applications:
(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one is used as a research compound for studying its potential role in the development and progression of certain diseases, such as cancer. Its presence in the human body and its physiological effects make it an important subject of investigation for understanding its impact on health and disease.
Used in Pheromone Applications:
(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one is used as a pheromone to influence human behavior. Its effects on mood and stress regulation make it a potential candidate for use in pheromone-based products aimed at enhancing social interactions and communication.

InChI:InChI=1/C22H32O4/c1-12-9-15-16-6-8-22(26,13(2)23)21(16,4)11-18(25)19(15)20(3)7-5-14(24)10-17(12)20/h10,12,15-16,18-19,25-26H,5-9,11H2,1-4H3/t12-,15-,16-,18-,19+,20-,21-,22-/m0/s1

Upstream product

• 1882-82-2 17-hydroxy-pregn-4-ene-3,11,20-trione 
• 82332-00-1 11-oxomedroxyprogesterone 
• 50-23-7 HYDROCORTISONE 
• 74332-34-6 3,3;20,20-bis-ethanediyldioxy-17-hydroxy-pregn-5-en-11-one 
• 41870-77-3 3,3;20,20-bis-ethanediyldioxy-pregn-5-ene-11β,17-diol 
• 1625-39-4 11β,17α,21-trihydroxy-6α-methylpregna-4-ene-3,20-dione 
• 113251-88-0 5,11β,17-trihydroxy-6β-methyl-5α-pregnane-3,20-dione 

Downstream Products

• 1625-11-2 21-acetoxy-11β,17-dihydroxy-6α-methyl-pregn-4-ene-3,20-dione 
• 1625-39-4 11β,17α,21-trihydroxy-6α-methylpregna-4-ene-3,20-dione 
• 6870-94-6 11β,17α-dihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione 
• 53-36-1 methylprednisolone acetate 
• 83-43-2 Methylprednisolone 

Relevant academic research and scientific papers

A methylprednisolone production process and production apparatus (by machine translation)

The invention discloses a methylprednisolone production device, including connected according to the procedure of the reaction, shui xifu, centrifugal filtration equipment, the concentrator, [...], biological fermentation tank, drying apparatus, the drying apparatus comprises an outer cylinder, the drying cylinder, the inner cylinder; the bottom surface of the outer cylinder is provided with a motor, the rotation of the motor shaft is provided with a exhaust fan blade, type impeller, vortex impeller; exhaust fan leaf is arranged on the bottom surface of the drying cylinder between the cylinder and the outer cylinder; drum type impeller is arranged on the drying cylinder between the cylinder and an inner cylinder; vortex impeller is arranged on the bottom of the inner drum; [...] is set with infrared heating in; on the inner end center provided with a feed port; the outer tube side wall comprises an inner wall and the outer wall; the inner wall and the outer wall of the annular cavity formed between the interlayer; outlet at upper end of the sandwich cavity is provided with an annular baffle plate; the baffle plate is provided with a vent; the upper end of the baffle is provided with a rotatable air purifies the link. This invention can reduce the methylprednisolone intermediate product in the production process of the preparation time, realize methylprednisolone rapid high-quality production. (by machine translation)

Preparation method of 6a-methyl hydrocortisone

The invention provides a preparation method of 6a-methyl hydrocortisone. The preparation method comprises the steps that hydrocortisone prepared from 4-androstene-3,17-dione (called as 4AD for short) is adopted as a raw material to generate an acid catalytic reaction with triethyl orthoformate in an organic solvent, and etherate 3-ether enol hydrocortisone is obtained; the etherate generates a Manlixi reaction with N-methylaniline and formaldehyde in an organic solvent, and a methylene product 6-methylene hydrocortisone is obtained; the methylene product generates a catalytic hydrogenation reaction in an organic solvent, and 6a-methyl hydrocortisone is obtained. Compared with a production method achieved by taking a mold removal product obtained by processing diosgenin as a raw material, the method for producing 6a-methyl hydrocortisone has the advantages that raw material sources are wide, the processes are economical and environmentally friendly, production operation is easy and convenient, the synthetic route is short, and the product yield is high; by producing 6a-methyl hydrocortisone through the method, the production cost is reduced by 40%-50% compared with a traditional method; the solvents used in production can be recycled and cyclically reused, and implementation of industrialized production is promoted.