70558-10-0

Basic information

• Product Name: Piperazine, 1-[(3-chlorophenyl)phenylmethyl]-
• CAS NO: 70558-10-0
• Molecular Formula: C17H19ClN2
• Molecular Weight: 286.804
• Mol File: 70558-10-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-[(3-chlorophenyl)phenylmethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-[(3-chlorophenyl)phenylmethyl]-(70558-10-0)
• EPA Substance Registry System: Piperazine, 1-[(3-chlorophenyl)phenylmethyl]-(70558-10-0)

Safety Data

• Hazardous Substances Data: 70558-10-0(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 13391-39-4 3-chlorobenzhydryl chloride 

Downstream Products

• 661453-54-9 C₃₂H₃₁ClN₂O 
• 866562-71-2 2-{4-[(3-chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-N,N-diphenyl-acetamide 
• 878162-11-9 4-[(3-chloro-phenyl)-phenyl-methyl]-piperazine-1-carboxylic acid benzhydryl-amide 
• 866562-52-9 1-{4-[(3-chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-2-diphenylamino-ethanone 

Relevant articles and documents

HETEROCYCLIC COMPOUND AND H1 RECEPTOR ANTAGONIST

A heterocyclic compound useful as an antiallergic agent is provided. A compound represented by the following formula (1) or a salt thereof: wherein the ring A is a homocyclic or heterocyclic ring; the ring B is a heterocyclic ring which contains G and nitrogen atom N as constituent atoms thereof, wherein G is CH or N; R1 is a carbonyl group or an alkylene group; R2a and R2b are an alkyl group, a cycloalkyl group, an aryl group, or a heterocyclic group; X is an oxygen atom or a sulfur atom; Z is a hydroxyl group, an alkoxy group, a cycloalkyloxy group, an aryloxy group, an aralkyloxy group, an amino group, or an N-substituted amino group; and n is 0 or 1; with the proviso that when the ring A is a benzene ring or when the ring B is a piperazine ring, R1 is an alkylene group which may have a substituent.

Process for producing piperazinesulfonamide derivatives and salts thereof

A process for advantageously preparing a piperazinesulfonamide derivative represented by the general formula (III): wherein R1 is hydrogen atom, a straight or branched chain alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a halogen atom, hydroxyl group, trifluoromethyl group, nitro group or amino group; R2 is a phenyl group which may have as substituents on its phenyl ring 1 to 3 groups selected from the group consisting of an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a halogen atom, hydroxyl group, trifluoromethyl group, nitro group and amino group, 2-pyridyl group, 3-pyridyl group or 4-pyridyl group; each of R3 and R4 is independently hydrogen atom, a straight or branched chain alkyl group having 1 to 6 carbon atoms, a hydroxyalkyl group having 1 to 4 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, or a phenyl group which may be substituted; and Y is an alkylene group having 1 to 12 carbon atoms, and a salt thereof.