705967-95-9Relevant academic research and scientific papers
Thio-ether functionalized glycolipid amphiphilic compounds reveal a potent activator of SK3 channel with vasorelaxation effect
Sevrain, Charlotte M.,Fontaine, Delphine,Bauduin, Alicia,Guéguinou, Maxime,Zhang, Bei Li,Chant?me, Aurélie,Mahéo, Karine,Pasqualin, C?me,Maupoil, Véronique,Couthon, Hélène,Vandier, Christophe,Jaffrès, Paul-Alain
, p. 2753 - 2766 (2021)
The modulation of SK3 ion channels can be efficiently and selectively achieved by using the amphiphilic compound Ohmline (a glyco-glycero-ether-lipid). We report herein a series of Ohmline analogues featuring the replacement of one ether function by a thi
Synthesis and cytotoxic activity of two novel 1-dodecylthio-2-decyloxypropyl-3-phosphatidic acid conjugates with gemcitabine and cytosine arabinoside
Alexander, Richard L.,Morris-Natschke, Susan L.,Ishaq, Khalid S.,Fleming, Ronald A.,Kucera, Gregory L.
, p. 4205 - 4208 (2007/10/03)
Cytosine arabinoside (ara-C) and gemcitabine (dFdC) are two standard chemotherapy drugs used in the treatment of patients with various cancers. To alter the pharmacokinetic and pharmacodynamic properties of these molecules, we conjugated a synthetic phosp
