70601-38-6

Upstream product

• 50277-65-1 2-propynoyl chloride 
• 931-59-9 benzenesulfenyl chloride 
• 624-65-7 2-propynyl chloride 

Downstream Products

• 98729-73-8 (4-Methoxy-benzyl)-(3-phenylsulfanyl-prop-2-ynyl)-amine 
• 98729-68-1 (2S,3R)-2-Bromo-3-hydroxy-N-(4-methoxy-benzyl)-N-(3-phenylsulfanyl-prop-2-ynyl)-butyramide 
• 103841-76-5 (2R,3R)-3-Methyl-oxirane-2-carboxylic acid (4-methoxy-benzyl)-(3-phenylsulfanyl-prop-2-ynyl)-amide 
• 98729-69-2 (3S,4S)-1-(p-methoxybenzyl)-3-<(R)-1-hydroxyethyl>-4-phenylthioethynyl-2-azetidinone 
• 868519-89-5 (3-azidoprop-1-ynylsulfanyl)benzene 
• 868520-04-1 (E)-(3-azido-2-methoxyprop-2-enylsulfonyl)benzene 
• 868520-03-0 (E)-(3-azido-2-methoxyprop-2-enylsulfinyl)benzene 
• 866315-22-2 (3-azidoprop-1-ynylsulfonyl)benzene 
• 866315-16-4 (3-azidoprop-1-ynylsulfinyl)benzene 
• 868519-93-1 [(3-azidopropa-1,2-dienyl)sulfonyl]benzene 
• 868519-92-0 (3-azidopropa-1,2-dienylsulfinyl)benzene 

Relevant academic research and scientific papers

CYCLIZATION REACTION OF N-PROPARGYL EPOXYAMIDE TO ACETYLENIC 2-AZETIDINONE, A PRECURSOR TO THIENAMYCIN AND RELATED CARBAPENEMS

Base treatment of N-propargyl epoxyamide 5 afforded the acetylenic 3-(hydroxyethyl)-2-azetidinone 9a, which was subsequently transformed to phenyl thiolester 2, a versatile intermediate for the carbapenem synthesis.

α-Acetylenic derivatives of α-amino acids

Novel acetylenic derivatives of α-amino acids of the following general structure: STR1 wherein n is an integer of from 1 to 3; R is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl w