70610-10-5

Upstream product

• 17635-59-5 dihydropinosylvin monomethyl ether 
• 870-63-3 prenyl bromide 
• 70610-14-9 1,3-Dimethoxy-2-(3-methyl-2-butenyl)-5-phenethylbenzol 
• 78916-50-4 1,3-dimethoxy-5-(2-phenylethyl)benzene 
• 133462-91-6 1-(1,1-Dimethyl-prop-2-ynyloxy)-3-methoxy-5-phenethyl-benzene 
• 133462-92-7 1-(1,1-Dimethyl-allyloxy)-3-methoxy-5-phenethyl-benzene 
• 35302-70-6 3-methoxy-5-[(E)-2-phenylvinyl]phenol 
• 1111-97-3 3-chloro-3-methylbut-1-yne 

Downstream Products

• 14531-52-3 dihydropinosylvin 
• 133462-79-0 5-Methoxy-2,2-dimethyl-7-phenethyl-2H-chromene 
• 70610-14-9 1,3-Dimethoxy-2-(3-methyl-2-butenyl)-5-phenethylbenzol 
• 133462-53-0 (±)-6-phenethyl-2-(prop-1-en-2-yl)-2,3-dihydrobenzofuran-4-ol 
• 133462-54-1 2-Isopropenyl-4-methoxy-6-phenethyl-2,3-dihydro-benzofuran 
• 70610-15-0 2,2-dimethyl-5-hydroxy-7-(2-phenylethyl)chroman 
• 133462-34-7 2-isopropenyl-6-hydroxy-4-(2-phenylethyl)dihydrobenzofuran 

Relevant academic research and scientific papers

CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE

Provided are cajanine structure analogous compounds, synthesis method and pharmacological effects thereof, the compounds of the present invention having the structure as represented by general formulas I, II, III, IV and V. Also provided are pharmaceutical compositions containing the compounds as active ingredient, and uses thereof; the compounds of the present invention having the pharmacological activities such as anti-virus, anti-virus-infection, nerve protection, anti-metabolic-diseases and the like. Also provided is a chemical total synthesis preparation method of the natural products cajanine, cajanine A and cajanine C. The present invention lays a foundation for the in-depth study and development of the compounds as clinical drugs in the future.

CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE

Provided are cajanine structure analogous compounds, synthesis method and pharmacological effects thereof, the compounds of the present invention having the structure as represented by general formulas I, II, III, IV and V. Also provided are pharmaceutical compositions containing the compounds as active ingredient, and uses thereof; the compounds of the present invention having the pharmacological activities such as anti-virus, anti-virus-infection, nerve protection, anti-metabolic-diseases and the like. Also provided is a chemical total synthesis preparation method of the natural products cajanine, cajanine A and cajanine C. The present invention lays a foundation for the in-depth study and development of the compounds as clinical drugs in the future.

PRENYL BIBENZYLS FROM THE LIVERWORT RADULA KOJANA

Fourteen new bibenzyl derivatives have been isolated from the liverwort Radula kojana together with two previously known bis(bibenzyls) and their structures characterized by spectral and chemical evidence.Seven new bibenzyls, 3,5-dihydroxy-2-(3-methyl-2-b

Synthesis of bryophyte components 2. Syntheses of prenylated bibenzyl derivatives

Efficient and expeditious syntheses of the biologically active prenylated bibenzyl derivatives 1a-d are developed giving rise to their access on a preparative scale.

PRENYL BIBENZYLS FROM THE LIVERWORTS RADULA PERROTTETII AND RADULA COMPLANATA

A new dihydrobenzofuran and a new chromene derivatives have been isolated from the liverwort Radula perrottetii, together with the known 3,5-dihydroxy-2-(3-methyl-2-butenyl)bibenzyl, 2(R)-2-isopropenyl-6,7-dihydroxy-4-(2-phenylethyl)dihydrobenzofuran, 2,2-dimethyl-7-hydroxy-5-(2-phenylethyl)chromene, 3,5-dihydroxy-6-carbomethoxy-2-(3-methyl-2-butenyl)bibenzyl, three bis(bibenzyls) and perrottetins E, F and G.The structures of the new compounds have been characterized as 2(R)-2-isopropenyl-6-hydroxy-4-(2-phenylethyl)dihydrobenzofuran and 2,2-dimethyl-7,8-dihydroxy-5-(2-phenylethyl)chromene by 1H and 13C NMR spectral analysis and synthesis.The structures of the previously reported chalcone and three prenyl bibenzyls, perrottetins A, B and C, and the other two bibenzyls, isolated from R. perrottetii are revised by analysis of their 1H and 13C NMR data, difference NOE experiments and synthesis of their derivatives.Radulanin L, a new bibenzyl with a dihydrooxepin skeleton was isolated from R. complanata together with 2- and 4-(3-methyl-2-butenyl)-3,5-dihydroxybibenzyls and its structure elucidated by comparison of 1H and 13C NMR spectral data with those of radulanins A and H.The structures of the previously reported radulanins A and H isolated from R. complanata are confirmed as correct by difference NOE.Some prenyl-containing bibenzyls showed 5-lipoxygenase and calmodulin inhibitory activity and vasopressin antagonist activity.R. perrottetii is a chemically isolated species in the Radulaceae.