35302-70-6

Basic information

• Product Name: PINOSYLVIN MONO METHYL ETHER
• Synonyms: C10276;Pinosylvin methyl ether;(E)-3-Hydroxy-5-methoxystilbene;3-Hydroxy-5-Methoxystilbene;(E)-3-Methoxy-5-styrylphenol;(E)-3-Methoxy-5-(2-phenylethenyl)phenol;-3-Methoxy-5-styrylphenol;AKOS 223-24
• CAS NO: 35302-70-6
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.27
• Product Categories: Stilbenes (substituted)
• Mol File: 35302-70-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 405.8 °C at 760 mmHg
• Flash Point: 245.6 °C
• Appearance: /
• Density: 1.159 g/cm³
• Vapor Pressure: 3.63E-07mmHg at 25°C
• Refractive Index: 1.662
• Storage Temp.: Refrigerator
• Solubility: Benzene (Slightly), DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
• CAS DataBase Reference: PINOSYLVIN MONO METHYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: PINOSYLVIN MONO METHYL ETHER(35302-70-6)
• EPA Substance Registry System: PINOSYLVIN MONO METHYL ETHER(35302-70-6)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-36-51/53
• Safety Statements: 26-61
• RIDADR: UN 3077 9 / PGIII
• Hazardous Substances Data: 35302-70-6(Hazardous Substances Data)

Usage

General Description

Pinosylvin mono methyl ether is a natural chemical compound found in various plant species, including pine trees. It is a methylated derivative of pinosylvin, a stilbenoid compound known for its antioxidant and anti-inflammatory properties. Pinosylvin mono methyl ether has been studied for its potential health benefits, including its antimicrobial and antifungal properties. It has also shown promise as a potential therapeutic compound for various diseases and as a natural alternative to synthetic preservatives in food and cosmetic products. Its unique chemical structure and biological activities make it a subject of interest in the fields of pharmacology, medicine, and natural product chemistry.

InChI:InChI=1/C15H14O2/c1-17-15-10-13(9-14(16)11-15)8-7-12-5-3-2-4-6-12/h2-11,16H,1H3/b8-7+

Upstream product

• 1449-46-3 benzyltriphenylphosphonium bromide 
• 21956-56-9 (E)-3,5-dimethoxystilbene 
• 100-39-0 benzyl bromide 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 7311-34-4 3,5-dimethoxybenzaldehdye 

Downstream Products

• 21956-56-9 (E)-3,5-dimethoxystilbene 
• 64125-60-6 3-methoxy-4-(3-methylbut-2-enyl)-5-[(E)-2-phenylethylene]phenol 
• 64095-60-9 (E)-3-methoxy-2-(3-methylbut-2-en-1-yl)-5-styrylphenol 
• 133462-46-1 2-((E)-3,7-Dimethyl-octa-2,6-dienyl)-1,5-dimethoxy-3-phenethyl-benzene 
• 133462-42-7 3,5-dihydroxy-2-(3-methyl-2-butenyl)bibenzyl 
• 70610-15-0 2,2-dimethyl-5-hydroxy-7-(2-phenylethyl)chroman 
• 98156-06-0 dihydroamorphastilbol dimethyl ether 
• 133462-73-4 1,5-Dimethoxy-2-(3-methyl-but-2-enyl)-3-phenethyl-benzene 
• 133462-43-8 3-hydroxy-5-methoxy-2-(3-methyl-2-butenyl)bibenzyl 
• 133462-72-3 3-hydroxy-5-methoxy-2-(3-methyl-2-butenyl) bibenzyl 
• 133462-75-6 3,5-dihydroxy-2-(2,3-epoxy-3-methylbutyl)bibenzyl 
• 133462-79-0 5-Methoxy-2,2-dimethyl-7-phenethyl-2H-chromene 
• 133462-77-8 methyl ether 2,2-dimethyl-7-hydroxy-5-(2-phenylethyl)chromene 
• 78916-45-7 2,2-dimethyl-7-hydroxy-5-(2-phenylethyl) chroman 

Relevant articles and documents

Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor

A series of 31 resveratrol derivatives was designed, synthesized and evaluated for activation and inhibition of the TRPA1 channel. Most acted as activators and desensitizers of TRPA1 channels like resveratrol or allyl isothiocyanate (AITC). Compound 4z (HUHS029) exhibited higher inhibitory activity than resveratrol with an IC50 value of 16.1?μM. The activity of 4z on TRPA1 was confirmed in TRPA1-expressing HEK293 cells, as well as in rat dorsal root ganglia neurons by a whole cell patch clamp recording. Furthermore, pretreatment with 4z exhibited an analgesic effect on AITC-evoked TRPA1-related pain behavior in vivo.

An efficient palladium-catalyzed Negishi cross-coupling reaction with arylvinyl iodides: facile regioselective synthesis of E-stilbenes and their analogues

A general synthetic route for the Pd-catalyzed cross-coupling of an arylzinc reagent with arylvinyl iodides (Negishi cross-coupling) has been developed. The system permits efficient and selective preparation of E-stilbenes and their analogues. It also functions effectively at low levels of catalyst loading without the need for an additional ligand and tolerates a wide range of functional groups including heteroaromatic substrates. A systematic study of various parameters was performed and correlated with catalyst-substrate activity.

Pest control chemicals against pine wood nematodes

Disclosed are (1) pest control chemicals against the pine wood nematodes containing an extract from a pine tree with an organic solvent, (2) a repellent against the pine wood nematodes containing α-humulene or a mixture of α-humulene and β-bisabolene, (3) a repellent against the pine wood nematodes containing a mixture of α-pinene and calarene, (4) a nematicide against the pine wood nematodes containing methyl ferulate, (+)-pinoresinol or a mixture thereof, and (5) highly effective pest control chemicals against pine wood nematodes containing hydroxystilbenes or salts thereof which are prepared by synthesizing methoxystilbenes from benzyl phosphonates and methoxybenzaldehydes by a Wittig-Horner reaction, performing demethylation to obtain the hydroxystilbenes, and preparing the salts thereof by conventional methods if necessary.