70618-67-6

Usage

InChI:InChI=1/C11H14N4S/c1-3-7-13-11(16)15-14-9(2)10-6-4-5-8-12-10/h3-6,8H,1,7H2,2H3,(H2,13,15,16)/b14-9+

Upstream product

• 59742-91-5 2-acetylpyridine hydrazone 
• 57-06-7 N-allyl isothiocyanate 

Relevant academic research and scientific papers

Heterocyclic and aromatic thiosemicarbazones useful in the treatment of filariasis

This invention is directed to heterocyclic and aromatic thiosemicarbazonesseful in the treatment of filariasis and in an animal, including humans.

2-acetylpyridine thiosemicarbazone compositions as anitviral agents

This invention relates to various compositions, comprising a 2-acetylprid thiosemicarbazone and a diol, which are useful in the treatment of viral infections.

Transition metal complexes of the selenium analogs of 2-acetyl- and 2-propionylpyridine thiosemicarbazones useful for treating malarial infections and leukemia

This invention relates to novel transition metal complexes of 2-acetyl- and-propionylpyridine thiosemicarbazones, their selenium analogs. These compounds are useful as antimalarial and antileukemic agents. Also disclosed are several synthetic procedures u

2-acetyl- and 2-propionylpyridine selenosemicarbazones

This invention relates to novel 2-acetyl- and 2-propionylpyridine selenosemicarbazones. These compounds are useful as antimalarial and antileukemic agents. Also disclosed are several synthetic procedures used to prepare the selenosemicarbazones.

2-acetylpyridine thiosemicarbazones as antiviral agents

This invention relates to the use of various 2-acetylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom in the treatment of viral infections. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.

2-Acetyl-and 2-propionylpyridine thiosemicarbazones

This invention relates to various 2-acetyl- and 2-propionylpyridine thioscarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malari

2-Acetylpyridine thiosemicarbazones. 1. A new class of potential antimalarial agents

Based on the antimalarial properties observed for 2-acetylpyridine 4-phenyl-3-thiosemicarbazone (1), an extensive series of related thiosemicarbazones was prepared and tested against Plasmodium berghei in mice. Screening results indicated that the presence of the 2-pyridylethylidene group was critical and that certain phenyl, benzyl, phenethyl, or cycloalkyl groups at N4 of the thiosemicarbazone moiety also contribute to antimalarial activity.