70625-51-3Relevant academic research and scientific papers
Tandem reduction + cyclization of ortho-substituted cinnamic esters
Sass, Daiane Cristina,De Lucca Jr., Emílio Carlos,Da Silva Barbosa, Jader,De Oliveira, Kleber Thiago,Constantino, Mauricio Gomes
, p. 5371 - 5374 (2011)
Conjugate reduction of ortho-substituted cinnamic esters by Stryker's reagent to form copper enolates, followed by intramolecular aldol-type cyclization, successfully generated indane and tetralin rings in one pot efficiently. This tandem reaction is generally diastereoselective and provides good yields.
