70626-00-5Relevant academic research and scientific papers
Synthesis method of Z-type halogenated chalcone compound
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Paragraph 0084; 0086; 0087, (2018/12/13)
The invention relates to a synthesis method of a Z-type halogenated chalcone compound as shown in formula (III), characterized by comprising: by using a compound shown in formula (I) and a compound shown in formula (II) as reaction raw materials, using IPrAuCl as a catalyst, using AgSbF as an assistant and using 1,2-dichloroethane as a solvent, performing a reaction at the room temperature; andafter ending the reaction, carrying out post treatment on reaction liquid to obtain the Z-type halogenated chalcone compound as shown in formula (III). The synthesis method disclosed by the inventionis simple and short in step, mild in condition, very high in reaction speed, meanwhile, high in yield and good in regioselectivity, and is a green and economic reaction process; (The formulas are shown in the description.).
