70633-77-1

Basic information

• Product Name: (3S,4E)-(+)-3-Hydroxy-5-phenyl-4-pentensaeure-methylester
• Synonyms: (3S,4E)-(+)-3-Hydroxy-5-phenyl-4-pentensaeure-methylester
• CAS NO: 70633-77-1
• Molecular Weight: 206.241
• Mol File: 70633-77-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (3S,4E)-(+)-3-Hydroxy-5-phenyl-4-pentensaeure-methylester(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4E)-(+)-3-Hydroxy-5-phenyl-4-pentensaeure-methylester(70633-77-1)
• EPA Substance Registry System: (3S,4E)-(+)-3-Hydroxy-5-phenyl-4-pentensaeure-methylester(70633-77-1)

Safety Data

• Hazardous Substances Data: 70633-77-1(Hazardous Substances Data)

Upstream product

• 420089-28-7 (2E,4E)-5-Phenyl-penta-2,4-dienoic acid methyl ester 
• 104-55-2 3-phenyl-propenal 
• 14371-10-9 (E)-3-phenylpropenal 
• 77086-38-5 ketene t-butyldimethylsilyl methyl acetal 

Downstream Products

• 90664-04-3 (2R,3R,4E)-(-)-(3-Methoxy-2-methyl-5-phenyl-4-pentenyl)-p-toluolsulfonat 
• 90695-50-4 (2E,3R,4S,5E)-methyl 4-methoxy-2-(methoxymethylene)-3-methyl-6-phenylhex-5-enoate 
• 90664-02-1 (1E,3R,4R)-(-)-3-Methoxy-4-methyl-5--1-phenyl-1-penten 
• 90695-47-9 (3R,4S,5E)-(-)-4-Methoxy-3-methyl-6-phenyl-5-hexensaeure-methylester 
• 90664-01-0 (1E,3R,4R)-(+)-4-Methyl-5--1-phenyl-1-penten-3-ol 
• 90664-05-4 (3R,4S,5E)-(+)-4-Methoxy-3-methyl-6-phenyl-5-hexennitril 
• 90664-07-6 (1E,3R,4S)-(+)-5-Brom-3-methoxy-4-methyl-1-phenyl-1-penten 
• 90664-03-2 (2R,3R,4E)-(-)-3-Methoxy-2-methyl-5-phenyl-4-penten-1-ol 
• 90695-44-6 (2R,3R,4E)-(+)-2-Methyl-5-phenyl-4-penten-1,3-diol 
• 90695-43-5 (2R,3R,4E)-(-)-3-Methoxy-2-methyl-5-phenyl-4-pentensaeure-methylester 
• 86853-07-8 (2S,3R,4E)-(+)-3-Hydroxy-2-methyl-5-phenyl-4-pentensaeure-methylester 
• 90695-49-1 (+)-Oudemansin 
• 90695-45-7 (2R,3R,4E)-(+)-3-Hydroxy-2-methyl-5-phenyl-4-pentensaeure-methylester 

Relevant articles and documents

Configuration Sampling With Five-Membered Atropisomeric P,N-Ligands

Here we report a strategy for the systematic variation of atropisomeric C1-symmetric P,N ligands to incrementally change the position of the groups within the chiral pocket without modifying their steric parameters. More specifically, the effec

Enantioselective reformatsky process for preparing optically active alcohols, amines and derivatives thereof

A process is provided for preparing optically active alcohols, amines and derivatives thereof by reacting aldehydes or imines at a temperature of less than 15° C. in the presence of a chiral, enantiomerically pure auxiliary with an organozinc halide which is obtained from zinc and a reactive halogen compound, and water, acid or base, or an alkylating, arylating, acylating or silylating reagent is subsequently added.

Enantioselektive Reformatsky-Process for the preparation of optically active alcohols, amines and their derivatives

Preparation of optically active alcohol and amine compounds (Ia) and (Ib) involves enantioselective Reformatsky reaction of an aldehyde or imine compound (II) with an organo zinc halide compound and treating with water, acid, base or an alkylating, acylating, arylating or silylating reagent. Preparation of optically active alcohol and amine compounds (Ia) and (Ib) involves enantioselective Reformatsky reaction of an aldehyde or imine compound of formula R1R2C=W (II) with an organozinc halide (Ozh) prepared by reacting zinc with halo-R3R4C(X)l-Y (III), at below 15degreesC, and treating with water, acid, base or an alkylating, acylating, arylating or silylating reagent. Reaction of Ozh and (II) is in the presence of a chiral, enantiomerically pure auxiliary (Aux) that contains at least 2 nitrogen donor atoms and at least one cyclic group, provided that any protons in it have pKa over 18. R1, R2 = T; T = H or 1-30C hydrocarbyl (optionally substituted by halo or cyano and optionally with at least one non-adjacent methylene replaced by oxygen, CO, COO, OCO, OCOO, sulfur or NRx, and with at least one methine replaced by -N= or -P=); R3, R4 = halo or T; Rx = H or 1-30C hydrocarbyl (optionally substituted by halo and optionally with at least one non-adjacent methylene replaced by oxygen, CO, COO, OCO, OCOO, sulfur or NRx, and with at least one methine replaced by -N= or -P=); X = =CR1R2 or CR1=CR2, cis or trans; l = 0 or 1; W = O or NR6; R5 = H, alkyl, aryl, acyl or silyl; R6 = Si(R1)3 or T; Y = CN, COZ, SO2Z, PO(Z)2 or aromatic ring optionally with at least one methine replaced by -N= or -P=, optionally containing O, S or NH in the ring and optionally substituted by halo, cyano or 1-30C hydrocarbyl in which at least one methylene is replaced by oxygen, CO, COO, OCO, OCOO, sulfur or NRx; Z = H or 1-30C hydrocarbyl (optionally substituted by halo and optionally with at least one non-adjacent methylene replaced by oxygen, CO, COO, OCO, OCOO, sulfur or NRx, and with at least one methine replaced by -N= or -P=), OH, OR1, OSi(R1)3, NHR1 or NR1R2, and halo = chloro, bromo or iodo.