70639-28-0Relevant academic research and scientific papers
Method for synthesizing hydroxyacetone ester compound based on methylene aziridine
-
Paragraph 0041-0042, (2021/09/26)
The invention provides a method for synthesizing a hydroxyacetone ester compound based on methylene aziridine. The hydroxyacetone ester compound is synthesized from N-substituted methylene aziridine, carboxylic acid and water as raw materials. A highly toxic metal catalyst, a strong oxidant and a halogenating reagent are not used, the reaction can be carried out at room temperature, and the yield of the prepared hydroxyacetone ester compound is 70-95%. The method has the advantages of cheap and easily available initial raw materials, simple operation, mild conditions and no need of a catalyst.
1,2-Dibromoethane and KI mediated α-acyloxylation of ketones with carboxylic acids
Wang, Xujie,Li, Gangsheng,Yang, Yanan,Jiang, Jianshuang,Feng, Ziming,Zhang, Peicheng
supporting information, p. 711 - 714 (2019/09/30)
The 1,2-dibromoethane- and KI-mediated α-acyloxylation of ketones is reported in moderate to good yield without the use of transition metals and strong oxidants. Various acids are well tolerated with wide functional group compatibility. An 1,2-dibromoethane- and KI-catalysed reaction mechanism is proposed based on the results of control experiments.
Microwave-Enhanced Coupling of Carboxylic Acids with Liquid Ketones and Cyclic Ethers Using Tetrabutylammonium Iodide/ t-Butyl Hydroperoxide
Macías-Benítez, Pablo,Moreno-Dorado, F. Javier,Guerra, Francisco M.
, p. 6027 - 6043 (2020/05/22)
The oxidative coupling of carboxylic acids with liquid ketones and cyclic ethers has been accomplished in minutes using t-butyl hydroperoxide in the presence of tetrabutylammonium iodide under microwave irradiation in the absence of a solvent. In addition to drastically shortening the reaction times, the use of microwaves resulted, in general, in yields equal to or higher than those obtained by conventional heating.
KI-catalyzed α-acyloxylation of acetone with carboxylic acids
Wu, Ya-Dong,Huang, Bei,Zhang, Yue-Xin,Wang, Xiao-Xu,Dai, Jian-Jun,Xu, Jun,Xu, Hua-Jian
supporting information, p. 5936 - 5939 (2016/07/06)
The KI-catalyzed reaction of acetone with aromatic carboxylic acids is achieved, leading to α-acyloxycarbonyl compounds in good to excellent yields under mild reaction conditions. The present method exhibits good functional-group compatibility. Notably, t
