70650-94-1Relevant academic research and scientific papers
Synthesis of spiro[pyrrolidine or piperidine-3,9′-xanthenes] by anionic cycloacylation of carbamates
Quintás, Domingo,García, Alberto,Domínguez, Domingo
, p. 9291 - 9294 (2007/10/03)
Xanthene spiropyrrolidines and spiropiperidines were synthesized by a process in which the key step was intramolecular trapping of a xanthen-9-yl anion by a carbamate side-chain situated at the same position.
Reaktionen mit Aziridinen, XXII. Einstufensynthese von Pyrrolidonen durch Amidoethylierung einfacher Ester mit N-Acylaziridinen
Stamm, Helmut,Woderer, Anton,Wiesert, Wolfgang
, p. 32 - 48 (2007/10/02)
Sodium enolates of simple esters (2) react smoothly with N-acylaziridines (3) in THF forming 3-substituted 2-pyrrolidones 8.If the α-position of the ester carries more than one H-atom amidoethylated pyrrolidones can result.Whilst a simple butyrolactone behaves analogously amidoethylation of coumaranone furnished mono and bis amidoethyl derivatives of coumaranone besides a pyrrolidone. - In tert-butyl alcohol only extremly acidic esters like 1e and 1j could be amidoethylated.
