70654-63-6

Usage

Uses

Used in Organic Synthesis:
(4-bromonaphthalen-1-yloxy)(tert-butyl)dimethylsilane is used as a reagent or building block in the field of organic synthesis. Its structural composition allows it to participate in a range of chemical reactions, facilitating the formation of complex molecular structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (4-bromonaphthalen-1-yloxy)(tert-butyl)dimethylsilane is utilized as a protecting group for reactive functional groups in complex molecules. This temporary protection is crucial for preserving the integrity of these groups during multi-step synthesis processes, ensuring the successful creation of the desired pharmaceutical compounds.
Used in Materials Science:
(4-bromonaphthalen-1-yloxy)(tert-butyl)dimethylsilane also finds application in materials science, where it can be employed in the development of novel materials with specific properties. Its unique structure contributes to the creation of materials with tailored characteristics for various applications.
Used in the Production of Chemical Intermediates:
(4-bromonaphthalen-1-yloxy)(tert-butyl)dimethylsilane is also used in the production of various chemical intermediates, which are essential precursors in the synthesis of a wide range of specialty chemicals. The versatility of (4-bromonaphthalen-1-yloxy)(tert-butyl)dimethylsilane makes it a valuable asset in the development of new and innovative chemical products.

Upstream product

• 571-57-3 4-bromo-1-naphthol 
• 288-32-4 1H-imidazole 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 110-87-2 3,4-dihydro-2H-pyran 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 81-07-2 saccharin 

Relevant academic research and scientific papers

Practical oxidative dearomatization of phenols with sodium hypochlorite pentahydrate

A highly efficient and practical oxidative dearomatization of phenols using sodium hypochlorite pentahydrate as an inexpensive, strong oxidant is reported for the first time. The oxidation reactions proceeded very rapidly in the presence of water to give the desired products in excellent yields, and sodium chloride and water were the only by-products derived from the oxidant.

POLY AROMATIC SODIUM CHANNEL BLOCKERS

Polyaromatic sodium channel blockers represented by the formula: are provided where the structural variables are defined herein. The invention also includes a variety of compositions, combinations and methods of treatment using these inventive sodium channel blockers.

3-Substituted benz[d]isothiazole-1,1-dioxides

This invention relates to 3-(phenyl/naphthyl)-benz[d]isothiazole-1,1-dioxides wherein the 3-phenyl or the 3-naphthyl group is substituted in the para position with hydroxy blocked with certain protecting groups. These compounds are useful as intermediates in the synthesis of certain 3,3-disubstituted-2,3-dihydrobenz[d]isothiazole-1,1-dioxide dyes which find utility, for example, as photographic optical filter agents and filter agent precursors.

Benzisothiazole-1,1-dioxide and naphtho-1,2-thiazine-1,1-dioxide compounds

This invention relates to certain 3,3-di(4'-OP-carbocyclic aryl)-2,3-dihydrobenz[d]isothiazole-1,1-dioxides (and-2,3-dihydronaphtho[1,8-de]-1,2-thiazine-1,1-dioxides) and to the preparation thereof by reacting (a) at least 2 equivalents of (i) a 4'-OP-carbocyclic aryllithium compound wherein P is a protecting group compatible with organometallic reagents or (ii) a 4'-OP-carbocyclic arylMgE compound wherein P is a protecting group compatible with organometallic reagents and E is chloro, bromo or iodo and (b) 1 equivalent of a compound selected from a 3-chlorobenz[d] isothiazole-1,1-dioxide and a 3-chloronaphtho[1,8-de]-1,2-thiazine-1,1-dioxide to give the corresponding 3,3-di(4'-OP-carbocyclic aryl)-2,3-dihydrobenz[d]isothiazole-1,1-dioxide or the corresponding 3,3-di(4'-OP-carbocyclic aryl)-2,3-dihydronaphtho[1,8-de]-1,2-thiazine-1,1-dioxide, which compounds are useful in the synthesis of phenol and 1-naphthol sulfam(na)-phthaleins employed, for example, as photographic optical filter agents and filter agent precursors.

Sulfam (na) phthaleins

This invention relates to 1-naphthol sulfam(na)phthaleins possessing a carbonyl moiety on the N atom of sulfam(na)phthalein ring, which compounds find utility, for example, as antihalation and filter dyes in photographic products and processes.

Novel synthesis of 3,3-substituted dihydrobenzisothiazole-1,1-dioxides and -2,3-dihydronaphtho-1,2-thiazine-1,1-dioxides

This invention relates to a method of synthesizing certain 3-(carbocyclic aryl)-3-(4'-OP-carbocyclic aryl)-2,3-dihydrobenz[d]isothiazole-1,1-dioxides (and -2,3-dihydronaphtho[1,8-de]-1,2-thiazine-1,1-dioxides) by reacting (a) a 4-OP-carbocyclic aryllithium compound wherein P is a protecting group and (b) a 3-(carbocyclic aryl)benz[d]isothiazole-1,1-dioxide wherein said 3-(carbocyclic aryl) moiety is other than a 3-(4'-OP-carbocyclic aryl) moiety to give (c) the corresponding 3-carbocyclic aryl)-3-(4'-OP-carbocyclic aryl)-2,3-dihydrobenz[d]isothiazole-1,1-dioxide. The -2,3-dihydronaphtho[1,8-de]-1,2-thiazine-1,1-dioxides are prepared in the same manner by reacting a 3-(carbocyclic aryl)naphtho[1,8-de]-1,2-thiazine-1,1-dioxide with said 4'-OP-carbocyclic aryllithium compound. In a further embodiment, the compounds synthesized according to the foregoing method are reacted with a carboxylic acid halide to give the corresponding 2-carbonyl-substituted 2,3-dihydrobenz[d]isothiazole-1,1-dioxide (or -2,3-dihydronaphtho[1,8-de]-1,2-thiazine-1,1-dioxides) followed by removing the protecting group, P, with weak acid to yield certain phenol and 1-naphthol sulfam(na)phthaleins useful, e.g., as optical filter agents and filter agent precursors in photography.