70671-51-1

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
H-DL-ORN(Z)-OH is utilized as a key intermediate in the synthesis of peptide-based drugs due to its unique structure and properties. Its presence of a Z-configured double bond and its role as a derivative of ornithine contribute to the development of novel therapeutic agents with potential applications in various medical conditions.
Used in Organic Chemistry:
As a building block in organic chemistry, H-DL-ORN(Z)-OH is employed for the synthesis of various organic compounds. Its unique structure allows for the creation of new molecules with potential applications in different industries, including pharmaceuticals, materials science, and agrochemicals.
Used in Biochemical Studies:
H-DL-ORN(Z)-OH is also used in biochemical research to investigate the role of ornithine and its derivatives in various biological processes. Understanding its interactions with enzymes, proteins, and other biomolecules can provide insights into the development of new drugs and therapies targeting specific diseases and conditions.

Upstream product

• 359781-89-8 Boc-Orn(Cbz)-OH 
• 70-26-8 2,5-diaminopentanoic acid 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 37510-73-9 N,N'-[3,3'-(3,6-dioxo-piperazine-2,5-diyl)-dipropyl]-bis-carbamic acid dibenzyl ester 
• 97371-32-9 N⁵-benzyloxycarbonyl-DL-ornithine methyl ester; hydrochloride 
• 119027-79-1 L-β-benzyloxypropionyl-carbobenzoxyrnithine 
• 359781-89-8 Boc-Orn(Cbz)-OH 
• 62631-17-8 H-DL-Orn(Cbz)-OMe 
• 110375-68-3 N⁵-benzyloxycarbonyl-N²-(4-nitro-benzoyl)-ornithine 

Relevant academic research and scientific papers

Dihydoxyhexanoic acid derivatives, their intermediates, and methods of making

This invention relates to dihydroxyhexanoic acid derivatives and their intermediates, as well as to methods of preparing such compounds. Additionally, present invention relates to removing a protecting group from a protected amine wherein the method comprises reacting the protected amine with phosphoric acid.

Aqueous phosphoric acid as a mild reagent for deprotection of the t-butoxycarbonyl group

Aqueous phosphoric acid (85 wt%) is an efficient and mild reagent for the deprotection of N-BOC groups. Acid sensitive functionalities including benzyl and methyl esters, TBDMS ether, CBZ and isopropylidene groups are compatible with the reaction conditions. The reactions are high yielding, and the workup is convenient.

Inhibitors of nitric oxide biosynthesis

The present invention is a method of treating hypotension and shock using select ornithine or NG -arginine derivatives.