62631-17-8

Basic information

• Product Name: Methyl N-δ-benzyloxycarbonyl-L-ornithinate
• Synonyms: Methyl N-δ-benzyloxycarbonyl-L-ornithinate
• CAS NO: 62631-17-8
• Molecular Weight: 280.324
• Mol File: 62631-17-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Methyl N-δ-benzyloxycarbonyl-L-ornithinate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl N-δ-benzyloxycarbonyl-L-ornithinate(62631-17-8)
• EPA Substance Registry System: Methyl N-δ-benzyloxycarbonyl-L-ornithinate(62631-17-8)

Safety Data

• Hazardous Substances Data: 62631-17-8(Hazardous Substances Data)

Upstream product

• 70671-51-1 N⁵-benzyloxycarbonyl-DL-ornithine 
• 2480-95-7 methyl (S)-5-(((benzyloxy)carbonyl)amino)-2-((tertbutoxycarbonyl)amino)pentanoate 
• 2480-93-5 Boc-Orn(Z)-OH 
• 77-76-9 2,2-dimethoxy-propane 
• 501-53-1 benzyl chloroformate 
• 3184-13-2 L-ornithine hydrochloride 
• 67-56-1 methanol 
• 3304-51-6 N-carboxybenzyl-L-ornithine 
• 75-36-5 acetyl chloride 

Downstream Products

• 115436-58-3 1-<5'-<4''-(Benzyloxycarbonylamino)-1''-(S)-(methoxycarbonyl)-n-butylamino>-5'-deoxy-2',3'-O-isopropylidene-α-L-talo-furanurononitrile>uracil 
• 115436-52-7 1-<5'-<4''-(Benzyloxycarbonylamino)-1''-(S)-(methoxycarbonyl)-n-butylamino>-5'-deoxy-2',3'-O-isopropylidene-β-D-allo-furanurononitrile>uracil 
• 656248-71-4 (S)-5-Benzyloxycarbonylamino-2-[2-(5-octyloxy-naphthalen-1-yloxy)-acetylamino]-pentanoic acid methyl ester 
• 1160755-11-2 ((S)-4-amino-4-carbamoylbutyl)carbamic acid benzyl ester 
• 1160939-75-2 3,5-diamino-6-chloropyrazine-2-carboxylic acid [(S)-4-(3-phenylacetylaminopropyl)imidazolidin-(2E)-ylidene]amide 
• 1160939-74-1 3,5-diamino-6-chloropyrazine-2-carboxylic acid [(S)-4-(3-phenylmethanesulfonylaminopropyl)-imidazolidin-(2E)-ylidene]amide 
• 1160939-73-0 3,5-diamino-6-chloropyrazine-2-carboxylic acid [(S)-4-[3-(3-benzylureido)-propyl]-imidazolidin-(2E)-ylidene]-amide 
• 1160939-71-8 (3-{(S)-2-[(E)-3,5-diamino-6-chloropyrazine-2-carbonylimino]imidazolidin-4-yl}propyl)carbamic acid benzyl ester 
• 1160755-10-1 ((S)-4,5-diaminopentyl)carbamic acid benzyl ester 
• 948912-21-8 N-δ-benzyloxycarbonyl-N-α-bis(2-ethoxy-2-oxoethyl)-L-ornithine methyl ester 
• 47732-08-1 tert.-Butyloxycarbonyl-L-threonyl-N^δ-benzyloxycarbonyl-L-ornithin 
• 21887-68-3 tert.-Butyloxycarbonyl-L-threonyl-N^δ-benzyloxycarbonyl-L-ornithin-hydrazid 
• 33983-36-7 N²-(toluene-4-sulfonyl)-L-ornithine methyl ester 
• 197358-32-0 3-(2-{4-[3-(1H-benzoimidazol-2-ylamino)-propyl]-2,5-dioxo-imidazolidin-1-yl}-acetylamino)-2-benzyloxycarbonylamino-propionic acid tert-butyl ester 

Relevant articles and documents

A synthetic approach to 5/5/6-polycyclic tetramate macrolactams of the discodermide type

A flexible synthetic route to the 16-membered tetramate-embedding macrocyclic scaffold present in various polycyclic tetramate macrolactams (PTMs) was developed which differs from the seminal synthesis of ikarugamycin by Boeckman Jr. in protecting groups and the order of connections. We also devised a short approach to various stereoisomers of the 5/5/6-tricarbocyclic motif found in discodermide and other PTMs, starting from the Weiss’ diketone.

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

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Organic Compounds

A compound of Formula I in free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.