70672-82-1

Usage

Uses

Used in Organic Synthesis:
2(3H)-Benzoxazolone,5-bromo-3-methylis used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure allows for a wide range of chemical reactions, facilitating the creation of diverse chemical entities.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2(3H)-Benzoxazolone,5-bromo-3-methylis utilized as a starting material for the synthesis of pharmacologically active compounds. Its potential biological activities, such as its anti-cancer properties and enzyme inhibition capabilities, make it a promising candidate for the development of new drugs.
Used in Anti-Cancer Applications:
2(3H)-Benzoxazolone,5-bromo-3-methylis studied for its potential as an anti-cancer agent. It has shown promise in inhibiting the growth of certain types of cancer cells, making it a valuable compound in the search for novel cancer treatments.
Used in Enzyme Inhibition:
2(3H)-Benzoxazolone,5-bromo-3-methylhas also been investigated for its ability to inhibit specific enzymes, which can be crucial in the treatment of various diseases. By targeting these enzymes, 2(3H)-Benzoxazolone,5-bromo-3-methylmay contribute to the development of new therapeutic agents.

InChI:InChI=1/C8H6BrNO2/c1-10-6-4-5(9)2-3-7(6)12-8(10)11/h2-4H,1H3

Upstream product

• 14733-73-4 5-bromo-1,3-benzoxazol-2(3H)-one 
• 74-88-4 methyl iodide 
• 1885-14-9 phenyl chloroformate 
• 40925-68-6 2-amino-4-bromo-phenol 
• 857828-66-1 (5-bromo-2-hydroxy-phenyl)-carbamic acid phenyl ester 

Downstream Products

• 1161500-18-0 tert-butyl (S)-2-((S)-1-amino-3-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)piperidine-1-carboxylate 
• 1254319-27-1 (S)-tert-butyl 4-(1-amino-3-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)tetrahydro-2H-pyran-4-ylcarbamate 
• 1352152-02-3 (S)-tert-butyl 1-(1-amino-3-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)cyclohexylcarbamate 

Relevant academic research and scientific papers

AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY

An amino pyrimidine compound for inhibiting protein tyrosine kinase activity, a pharmaceutical composition thereof, preparation therefor, and an application thereof. Specifically, an amino pyrimidine compound represented by formula (I), R1, R2, L, Y, R6, W, A, m, and n being defined in the specification, and a pharmaceutically acceptable salt, a stereoisomer, a solvent compound, a hydrate, a polymorphism, a prodrug, or an isotope variant thereof. The compound can be used for treating and/or preventing protein tyrosine kinase-related diseases such as cell proliferative diseases, cancers, and immune diseases.

PYRIMIDODIAZEPINONE DERIVATIVE

The invention provides a pyrimidodiazepinone derivative represented by the general formula (I) [wherein n represents 1 or 2, Z represents a hydrogen atom or the like, R1 and R2 may be the same or different, and each represents a hydrogen atom or the like, A represents a bond, (CH2)m (wherein m represents an integer of 1 to 4), optionally substituted phenylene, optionally substituted pyridinediyl, or C=O, R3 represents a hydrogen atom, optionally substituted lower alkyl, or the like, and R4 represents a hydrogen atom or the like], or a pharmaceutically acceptable salt thereof or the like.

BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYMTHASE INHIBITORS

The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical comp