2(3H)-Benzoxazolone,5-bromo-3-methyl-

Base Information

• Chemical Name: 2(3H)-Benzoxazolone,5-bromo-3-methyl-
• CAS No.: 70672-82-1
• Molecular Formula: C8H6 Br N O2
• Molecular Weight: 228.045
• Mol file: 70672-82-1.mol

Synonyms:5-Bromo-3-methylbenzo[d]oxazol-2(3H)-one;5-Bromo-3-methylbenzoxazolin-2-one; NSC 355408

Chemical Property of 2(3H)-Benzoxazolone,5-bromo-3-methyl-

Chemical Property:

• Vapor Pressure: 0.00052mmHg at 25°C
• Boiling Point: 312.7°Cat760mmHg
• Flash Point: 142.9°C
• PSA: 35.14000
• Density: 1.71g/cm³
• LogP: 1.89400

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-3-methylbenzo[d]oxazol-2(3H)-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2(3H)-Benzoxazolone,5-bromo-3-methyl-

There total 5 articles about 2(3H)-Benzoxazolone,5-bromo-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.5%

5-bromo-1,3-benzoxazol-2(3H)-one (14733-73-4) + methyl iodide (74-88-4) → 5-bromo-3-methylbenzo[d]oxazole-2(3H)-one (70672-82-1)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 20 ℃;

Reference yield:

2-amino-4-bromo-phenol (40925-68-6) → 5-bromo-3-methylbenzo[d]oxazole-2(3H)-one (70672-82-1)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether

2: aqueous KOH

With potassium hydroxide; diethyl ether;

DOI:10.1021/ja01322a038

Reference yield:

(5-bromo-2-hydroxy-phenyl)-carbamic acid phenyl ester (857828-66-1) → 5-bromo-3-methylbenzo[d]oxazole-2(3H)-one (70672-82-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous KOH

With potassium hydroxide;

DOI:10.1021/ja01322a038

upstream raw materials:

5-bromo-1,3-benzoxazol-2(3H)-one

methyl iodide

phenyl chloroformate

2-amino-4-bromo-phenol

Downstream raw materials:

(S)-tert-butyl 1-(1-amino-3-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)cyclohexylcarbamate

(S)-tert-butyl 4-(1-amino-3-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)tetrahydro-2H-pyran-4-ylcarbamate

tert-butyl (S)-2-((S)-1-amino-3-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)piperidine-1-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 70672-82-1 2(3H)-Benzoxazolone,5-bromo-3-methyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send