70678-07-8Relevant academic research and scientific papers
REDUCTION DE DERIVES D'ALCOOLS PROPARGYLIQUES CATALYSEE PAR UN COMPLEXE DE PALLADIUM ZEROVALENT
Colas, Yann,Cazes, Bernard,Gore, Jacques
, p. 165 - 173 (2007/10/02)
Catalysis by tetrakis(triphenylphosphine)palladium of the reaction of hydride donnors with secondary propargylic bromides, mesylates and phosphates increases markedly the amount of allene produced.The best results in that direction are obtained with mesylates and phosphates by using lithium triethylborohydride.The reaction then occurs with an ANTI introduction of the hydride with respect to the leaving group.A mechanism is proposed which explains the influence of the various parameters of the reaction.
