70682-04-1Relevant academic research and scientific papers
Asymmetric spirocyclization: A new type of acid-catalyzed intramolecular 1,4-addition to form carba-spirocyclic compounds
Yamada, Satoshi,Karasawa, Satoru,Takahashi, Youichi,Aso, Mariko,Suemune, Hiroshi
, p. 15555 - 15566 (1998)
Novel spirocyclization based on intramolecular 1,4-addition and its asymmetric version have been developed using a combination of Lewis acid and 1,2-diol. Treatment of five- and six-membered α,β-unsaturated cyclic ketones having a 4-oxopentyl group at the
