70691-95-1Relevant academic research and scientific papers
Continuous-flow azide-alkyne cycloadditions with an effective bimetallic catalyst and a simple scavenger system
?tv?s, Sndor B.,Hatoss, Gbor,Georgides, dm,Kovcs, Szabolcs,Mndity, Istvn M.,Novk, Zoltn,Fül?p, Ferenc
, p. 46666 - 46674 (2014/12/10)
A flow chemistry-based technique is presented herein for Cu(i)-catalyzed azide-alkyne cycloadditions with a copper on iron bimetallic system as the catalyst and iron powder as a readily available copper scavenger. The method proved to be rapid and safe as
Synthesis of noncondensed polynuclear vicinal triazoles
Tikhonova,Serebryakova,Maksikova,Gareev,Vereshchagin
, p. 1241 - 1244 (2007/10/02)
The reaction of propargyl alcohol and butynediol with organic mono- and diazides gave N-alkyl-C-hydroxymethyl-1,2,3-triazoles, the hydroxy group of which was transformed successively to a halo group and an azide fragment. Two- and three-ring triazole stru
UNSATURATED CARBONYL-CONTAINING COMPOUNDS. XXVIII. CYCLOADDITION OF ORGANIC AZIDES TO α-ACETYLENIC KETONES AND ACIDS
Vereshchagin, L. I.,Tikhonova, L. G.,Maksikova, A. V.,Serebryakova, E. S.,Proidakov, A. G.,Filippova, T. M.
, p. 641 - 648 (2007/10/02)
The reaction of α-acetylenic ketones and acids with organic azides leads to the formation of 1-alkyl(aryl)-4-acyl(carboxy)-1,2,3-triazoles or to a mixture of the 1,4- and 1,5-disubstituted isomers.The effect of the structure of the initial compound and of the solvent on the direction of cycloaddition was investigated.
