77177-20-9Relevant academic research and scientific papers
Metal-Free Intermolecular Azide-Alkyne Cycloaddition Promoted by Glycerol
Rodríguez-Rodríguez, Marta,Gras, Emmanuel,Pericàs, Miquel A.,G?mez, Montserrat
, p. 18706 - 18710 (2015)
Metal-free intermolecular Huisgen cycloadditions using nonactivated internal alkynes have been successfully performed in neat glycerol, both under thermal and microwave dielectric heating. In sharp contrast, no reaction occurs in other protic solvents, su
New mono- and bidentate P-ligands using one-pot click-chemistry: Synthesis and application in Rh-catalyzed hydroformylation
Dubrovina, Natalia V.,Domke, Lutz,Shuklov, Ivan A.,Spannenberg, Anke,Franke, Robert,Villinger, Alexander,B?rner, Armin
, p. 8809 - 8817 (2013/09/23)
Three families of new phosphorus ligands have been prepared using the click-chemistry approach proceeding in only two steps and without intermediate P-protection. The methodology allows the high yield production of mono- and bidentate P-ligands, bearing at least one P-O bond. The ligands were tested in the Rh-catalyzed hydroformylation of 1-octene.
CYCLOADDITION OF FUNCTIONALLY SUBSTITUTED AZIDES TO ACETYLENIC ALCOHOLS
Tikhonova, L. G.,Serebryakova, E. S.,Maksikova, A. V.,Chernysheva, G. V.,Vereshchagin, L. I.
, p. 1244 - 1248 (2007/10/02)
The corresponding hydroxymethyl-1,2,3-triazoles were obtained by the reaction of monosubstituted and disubstituted acetylenic alcohols with a wide range of organic azides.It was shown that the reaction of azidoacetic acid with acetylenic keto alcohols is accompanied by the formation of triazolooxazines; sterically hindered azides do not add to the acetylenic carbinols; azido ketones are converted in the reaction into urethane and carbanilide.
SYNTHESIS OF 1-ALKYL-4(5)-HYDROXYMETHYL-1,2,3-TRIAZOLES
Maksikova, A. V.,Serebryakova, E. S.,Tikhonova, L. G.,Vereshchagin, L. I.
, p. 1284 - 1285 (2007/10/02)
An in situ method for the synthesis 1-alkyl-4(5)-hydroxymethyl-1,2,3-triazoles by the action of acetylenic alcohols with alkyl azides as the latter are formed from sodium azide and alkyl halides in dimethylformamide is proposed.
UNSATURATED CARBONYL-CONTAINING COMPOUNDS. XXVIII. CYCLOADDITION OF ORGANIC AZIDES TO α-ACETYLENIC KETONES AND ACIDS
Vereshchagin, L. I.,Tikhonova, L. G.,Maksikova, A. V.,Serebryakova, E. S.,Proidakov, A. G.,Filippova, T. M.
, p. 641 - 648 (2007/10/02)
The reaction of α-acetylenic ketones and acids with organic azides leads to the formation of 1-alkyl(aryl)-4-acyl(carboxy)-1,2,3-triazoles or to a mixture of the 1,4- and 1,5-disubstituted isomers.The effect of the structure of the initial compound and of the solvent on the direction of cycloaddition was investigated.
