7071-45-6Relevant academic research and scientific papers
Synthesis and chemical reactivity of 3-oxo-2-arylhydrazono-propanenitriles
Abdallah, Sanaa O.,Metwally, Nadia H.,Anwar, Hany F.,Elnagdi, Mohamed H.
, p. 781 - 786 (2007/10/03)
2-Formyl-2-arylhydrazonoethanenitriles 6b-d where prepared via reacting enaminonitrile 2b,c with aromatic diazonium salts. These reacted with phenylhydrazine to yield bis hydrazones that were converted to arylazopyrazoles via a novel Vilsmeier-Haack reaction type. Reaction of 6c with hydroxylamine afforded oxime that could be successfully cyclised into arylazoisoxazole. Reaction of 6c with hydrazine hydrate to yield arylazoaminopyrazole that proved to be excellent precursors for synthesis functional substituted pyrazolopyrimidines.
Studies with functionally substituted enamines: Synthesis of new aminoazolo-pyrimidines and -1,2,4-triazines
Ghozlan, Said Ahmed Soliman,Abdelhamid, Ismail Abdelshafy,Gaber, Hatem,Elnagdi, Mohamed Hilmy
, p. 789 - 793 (2007/10/03)
3-Aminoacrylonitrile derivatives (1d-g) coupled with aromatic and heteroaromatic diazonium salts yielding arylhydrazonals and pyrazolo[5,1-c] triazines. The enaminonitriles 1d-g condensed to form dienes 6a-c on reflux in acetic acid. The latter underwent Diels-Alder type addition to naphthoquinone. Aminopyrazolopyrimidines were obtained from reaction of 1d-g with heteroaromatic aminoazoles. Enaminonitrile 1d formed pyran 21 with benzylidenemalononitrile, and dihydropyrimidine 22 with benzaldehyde and urea.
Reactions of Methylenedisulfonyldi(acetic acid) Derivatives with Arenediazonium Salts and Aromatic Aldehydes
Bazavova, I. M.,Esipenko, A. N.,Neplyuev, V. M.,Lozinskii, M. O.
, p. 520 - 524 (2007/10/03)
Reactions of methylenedisulfonyldiacetonitrile with arenediazonium salts in weakly alkaline medium yield mixtures of 1,5-bis(arylhydrazono)-1,5-dicyano-2,4-dithiapentane 2,2,4,4-tetraoxides and 1,5-diaryl-3-cyanoformazans.Under the same conditions, dimethyl methylenedisulfonyldiacetate yields mainly 1,5-bis(arylhydrazono)-1,5-bis(methoxycarbonyl)-2,4-dithiapentane 2,2,4,4-tetraoxides, whereas methylenedisulfonyldiacetamide reacts with elimination of the carbamoyl groups to give 1,1',5,5'-tetraaryl-3,3'-methylenedisulfonyldiformazans.Methylenedisulfonyldiacetonitrile reacts with aromatic aldehydes with formation of 1,7-diaryl-2,6-dicyano-3,5-dithia-1,6-heptadiene 3,3,5,5-tetraoxides.
Convenient Synthesis of 3-Arylazopyrazoles and 2-Arylazo-1,3,4-Δ2-Thiadiazoline Derivatives from 3-Nitroformazans
Abdelhamid, Abdou O.,Abbas, Ikhlass M.,Abdallah, Magda A.,Fahmi, Abdelgawad A.,Shawali, Ahmad S.
, p. 813 - 816 (2007/10/02)
Reactions of 3-nitro-1,5-diarylformazans 1a-c with carbanions of acetylacetone, dibenzoylmethane, acetoacetanilide, benzoylacetonitrile, ω-benzenesulfonylacetophenone and malononitrile yielded the corresponding 3-arylazopyrazole derivatives 4-9 respective
