70753-36-5

Usage

Uses

Used in Organic Synthesis:
5-Isoxazolecarboxaldehyde, 3-methyl(6CI, 7CI, 9CI) is used as a versatile building block in organic synthesis for the creation of various heterocyclic compounds. Its unique structure and reactivity make it a valuable component in the formation of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-Isoxazolecarboxaldehyde, 3-methyl(6CI, 7CI, 9CI) is utilized as a starting material for the preparation of biologically active molecules. Its potential in the development of new drugs and pharmaceuticals is attributed to its ability to contribute to the synthesis of compounds with therapeutic properties.
Used in Pharmaceutical Research and Development:
5-Isoxazolecarboxaldehyde, 3-methyl(6CI, 7CI, 9CI) plays a pivotal role in pharmaceutical research and development, where it is employed for exploring its potential in the synthesis of novel drug candidates. Its unique chemical properties allow researchers to innovate and discover new therapeutic agents with improved efficacy and selectivity.
Used in Drug Discovery:
5-Isoxazolecarboxaldehyde, 3-methyl(6CI, 7CI, 9CI) is also used in drug discovery processes, where it aids in the identification and optimization of lead compounds. Its reactivity and structural features are harnessed to design molecules with desired pharmacological activities, contributing to the advancement of new treatment options for various diseases.
Overall, 5-Isoxazolecarboxaldehyde, 3-methyl(6CI, 7CI, 9CI) is an important chemical compound with diverse applications in the field of chemistry and pharmaceutical research, making significant contributions to the synthesis of biologically active molecules and the development of innovative pharmaceuticals.

InChI:InChI=1/C5H5NO2/c1-4-2-5(3-7)8-6-4/h2-3H,1H3

Upstream product

• 14716-89-3 3-methyl-5-isoxazolemethanol 
• 683-58-9 acetohydroximoyl chloride 
• 124237-06-5 1,1-diethoxy-2,4-pentandione 
• 1004-96-2 3-methylisoxazole-5-carboxylic acid methyl ester 
• 64-17-5 ethanol 
• 7803-49-8 hydroxylamine 
• 53009-77-1 1,1-dichloro-pentane-2,4-dione 
• 4857-42-5 3-methyl-5-isoxazolecarboxylic acid 
• 215360-91-1 3-Methyl-5-trimethylsilanyloxymethyl-isoxazole 
• 27930-43-4 5-dichloromethyl-3-methyl-isoxazole 

Downstream Products

• 55086-61-8 5-acetyl-3-methylisoxazole 
• 100114-42-9 amino-(3-methyl-isoxazol-5-yl)-acetic acid 
• 4857-42-5 3-methyl-5-isoxazolecarboxylic acid 
• 157555-78-7 3-methyl-5-<2-methyl-4-(toluene-4-sulphonyl)-4,5-dihydrooxazol-5-yl>isoxazole 
• 1053720-00-5 3-Methyl-5-[2-((E)-2-methyl-3-{(2S,3S,4R,5S)-5-[(2S,3S)-3-((1R,2S)-1-methyl-2-trimethylsilanyloxy-propyl)-oxiranylmethyl]-3,4-bis-trimethylsilanyloxy-tetrahydro-pyran-2-yl}-propenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazol-5-yl]-isoxazole 
• 169779-51-5 5-(3-methyl-5-isoxazolyl)oxazole 
• 100959-34-0 2-amino-3-(3-methyl-isoxazol-5-yl)-propionic acid 
• 1428972-57-9 3-methoxy-N-((3-methylisoxazol-5-yl)methylene)aniline 
• 1428968-85-7 1-(1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-(3-methylisoxazol-5-yl)ethanone 
• 1578301-23-1 C₁₆H₁₆N₂O₃ 
• 7063-93-6 3-methyl-5-vinylisoxazole 
• 1600563-07-2 (2,4-dichloro-3-phenylquinolin-6-yl)(3-methylisoxazol-5-yl)methanol 
• 1191255-69-2 C₂₂H₂₃N₅O₃ 
• 72418-41-8 (3-methyl-isoxazol-5-yl)-oxo-acetaldehyde oxime 

Relevant academic research and scientific papers

CONDENSED AZINES FOR EP300 OR CBP MODULATION AND INDICATIONS THEREFOR

Disclosed are compounds of Formula I or a pharmaceutically acceptable salt, a solvate, a tautomer, a stereoisomer or a deuterated analog thereof, wherein A1, A2, A3, A4, R4, X1, X2, and X3 are as described in any of the embodiments described in this disclosure; compositions thereof; and uses thereof.

INTEGRASE INHIBITORS 3

The present invention provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Compounds of formula (I) are also provided.

Hydroboration-azide alkylation as efficient tandem reactions for the synthesis of chiral non racemic substituted pyrrolidines

The synthesis of chiral non racemic substituted pyrrolidines from homoallylic alcohols is presented. These precursors are readily converted via the azides to the corresponding pyrrolidines using hydroboration-cycloalkylation tandem reactions as key steps.

The chemistry of pseudomonic acid part 14. Synthesis and in vivo biological activity of heterocyclyl substituted oxazole derivatives

Semisynthetic analogues of pseudomonic acid A have been prepared containing a heterocyclyl substituted oxazole. Derivatives in which the heterocycle was thiophene, furan, pyridine, or isoxazole showed good antibacterial potency and were further evaluated in vivo. Both pharmacokinetic parameters and oral activity against an experimental intraperitoneal sepsis were superior to results obtained from previously described pseudomonic acid A derivatives.

Stereoselectivity in the Peterson reaction - Application to the synthesis of BRL 49467

The E:Z selectivity in the introduction of the tri-substituted double bond in BRL 49467 could be controlled by the choice of base and silyl group used in a Peterson olefination reaction. The method allowing optimum E-selectivity was developed such that it

Hypoglycemic 5-substituted oxazolidine-2,4-diones

Hypoglycemic 5-chromanyl, 2,3-dihydro-5-benzo[b]furanyl, 5-pyridyl, 5-quinolyl, 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolyl oxazolidine-2,4-diones and the pharmaceutically acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.