70753-36-5

Basic information

• Product Name: 5-Isoxazolecarboxaldehyde, 3-methyl- (6CI, 7CI, 9CI)
• Synonyms: 5-Isoxazolecarboxaldehyde, 3-methyl- (6CI, 7CI, 9CI);3-METHYLISOXAZOLE-5-CARBALDEHYDE;3-methyl-5-isoxazolecarbaldehyde(SALTDATA: FREE);3-Methyl-5-isoxazolecarbaldehyde
• CAS NO: 70753-36-5
• Molecular Formula: C₅H₅NO₂
• Molecular Weight: 111.1
• Product Categories: ALDEHYDE
• Mol File: 70753-36-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 180-182 °C
• Boiling Point: 218.759 °C at 760 mmHg
• Flash Point: 86.103 °C
• Appearance: /
• Density: 1.19 g/cm³
• Vapor Pressure: 0.124mmHg at 25°C
• Refractive Index: 1.516
• PKA: -3.14±0.50(Predicted)
• CAS DataBase Reference: 5-Isoxazolecarboxaldehyde, 3-methyl- (6CI, 7CI, 9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoxazolecarboxaldehyde, 3-methyl- (6CI, 7CI, 9CI)(70753-36-5)
• EPA Substance Registry System: 5-Isoxazolecarboxaldehyde, 3-methyl- (6CI, 7CI, 9CI)(70753-36-5)

Safety Data

• Statements: 43-50
• Safety Statements: 36/37-61
• HazardClass: IRRITANT
• Hazardous Substances Data: 70753-36-5(Hazardous Substances Data)

Usage

General Description

5-Isoxazolecarboxaldehyde, 3-methyl- is a chemical compound with the molecular formula C5H5NO2. It is a derivative of isoxazole and carboxaldehyde, and it is commonly used in organic synthesis and medicinal chemistry. 5-Isoxazolecarboxaldehyde, 3-methyl- (6CI, 7CI, 9CI) is a versatile building block for the synthesis of various biologically active molecules and pharmaceuticals. It can be used as a starting material for the preparation of various heterocyclic compounds. Additionally, it has potential applications in the development of new drugs and pharmaceuticals due to its unique chemical properties and reactivity. Overall, 5-Isoxazolecarboxaldehyde, 3-methyl- is an important chemical compound with diverse applications in the field of chemistry and pharmaceutical research.

InChI:InChI=1/C5H5NO2/c1-4-2-5(3-7)8-6-4/h2-3H,1H3

Upstream product

• 14716-89-3 3-methyl-5-isoxazolemethanol 
• 683-58-9 acetohydroximoyl chloride 
• 1004-96-2 3-methylisoxazole-5-carboxylic acid methyl ester 
• 64-17-5 ethanol 
• 124237-06-5 1,1-diethoxy-2,4-pentandione 
• 7803-49-8 hydroxylamine 
• 4857-42-5 3-methyl-5-isoxazolecarboxylic acid 
• 53009-77-1 1,1-dichloro-pentane-2,4-dione 
• 215360-91-1 3-Methyl-5-trimethylsilanyloxymethyl-isoxazole 
• 27930-43-4 5-dichloromethyl-3-methyl-isoxazole 

Downstream Products

• 55086-61-8 5-acetyl-3-methylisoxazole 
• 100114-42-9 amino-(3-methyl-isoxazol-5-yl)-acetic acid 
• 4857-42-5 3-methyl-5-isoxazolecarboxylic acid 
• 1053720-00-5 3-Methyl-5-[2-((E)-2-methyl-3-{(2S,3S,4R,5S)-5-[(2S,3S)-3-((1R,2S)-1-methyl-2-trimethylsilanyloxy-propyl)-oxiranylmethyl]-3,4-bis-trimethylsilanyloxy-tetrahydro-pyran-2-yl}-propenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazol-5-yl]-isoxazole 
• 169779-51-5 5-(3-methyl-5-isoxazolyl)oxazole 
• 7063-93-6 3-methyl-5-vinylisoxazole 
• 1600563-07-2 (2,4-dichloro-3-phenylquinolin-6-yl)(3-methylisoxazol-5-yl)methanol 
• 1578301-23-1 C₁₆H₁₆N₂O₃ 
• 1428968-85-7 1-(1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-(3-methylisoxazol-5-yl)ethanone 
• 1428972-57-9 3-methoxy-N-((3-methylisoxazol-5-yl)methylene)aniline 
• 1191255-69-2 C₂₂H₂₃N₅O₃ 
• 72418-41-8 (3-methyl-isoxazol-5-yl)-oxo-acetaldehyde oxime 
• 100959-34-0 2-amino-3-(3-methyl-isoxazol-5-yl)-propionic acid 
• 157555-82-3 3-Methyl-5-{2-[(triphenylsilanyl)-methyl]-oxazol-5-yl}-isoxazole 

Relevant articles and documents

CONDENSED AZINES FOR EP300 OR CBP MODULATION AND INDICATIONS THEREFOR

Disclosed are compounds of Formula I or a pharmaceutically acceptable salt, a solvate, a tautomer, a stereoisomer or a deuterated analog thereof, wherein A1, A2, A3, A4, R4, X1, X2, and X3 are as described in any of the embodiments described in this disclosure; compositions thereof; and uses thereof.

Hydroboration-azide alkylation as efficient tandem reactions for the synthesis of chiral non racemic substituted pyrrolidines

The synthesis of chiral non racemic substituted pyrrolidines from homoallylic alcohols is presented. These precursors are readily converted via the azides to the corresponding pyrrolidines using hydroboration-cycloalkylation tandem reactions as key steps.

Stereoselectivity in the Peterson reaction - Application to the synthesis of BRL 49467

The E:Z selectivity in the introduction of the tri-substituted double bond in BRL 49467 could be controlled by the choice of base and silyl group used in a Peterson olefination reaction. The method allowing optimum E-selectivity was developed such that it