7076-17-7

Basic information

• Product Name: 1,3,4,5-TETRAHYDROTHIOPYRANO[4,3-B]INDOLE
• Synonyms: 1,3,4,5-TETRAHYDROTHIOPYRANO[4,3-B]INDOLE
• CAS NO: 7076-17-7
• Molecular Formula: C₁₁H₁₁NS
• Molecular Weight: 189.28
• Mol File: 7076-17-7.mol
• Article Data: 10

Chemical Properties

• Melting Point: 157 °C
• Boiling Point: 382°C at 760 mmHg
• Flash Point: 184.8°C
• Appearance: /
• Density: 1.277g/cm³
• Vapor Pressure: 1.07E-05mmHg at 25°C
• Refractive Index: 1.725
• PKA: 17.12±0.20(Predicted)
• CAS DataBase Reference: 1,3,4,5-TETRAHYDROTHIOPYRANO[4,3-B]INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4,5-TETRAHYDROTHIOPYRANO[4,3-B]INDOLE(7076-17-7)
• EPA Substance Registry System: 1,3,4,5-TETRAHYDROTHIOPYRANO[4,3-B]INDOLE(7076-17-7)

Safety Data

• Hazardous Substances Data: 7076-17-7(Hazardous Substances Data)

Usage

Chemical class

It belongs to the indole class of organic molecules.

Structural configuration

Characterized by a thiopyrano ring fused to the indole ring.

Potential applications

Has potential applications in the field of medicinal chemistry.

Pharmaceutical development

Particularly useful in the development of new pharmaceutical drugs.

Biological activities

May exhibit antimicrobial, anticancer, or anti-inflammatory properties.

Subject of interest

A subject of interest for further research and development.

Distinctive structure

Its unique structural configuration makes it an intriguing target for study.

Reactivity

Its distinctive structure and reactivity make it a target for synthetic chemistry and organic synthesis studies.

InChI:InChI=1/C11H11NS/c1-2-4-10-8(3-1)9-7-13-6-5-11(9)12-10/h1-4,12H,5-7H2

Upstream product

• 1072-72-6 Tetrahydrothiopyran-4-one 
• 59-88-1 phenylhydrazine hydrochloride 
• 100-63-0 phenylhydrazine 
• 95389-34-7 1,3,4,4a,5,9b-hexahydro-thiopyrano[4,3-b]indole 
• 19090-03-0 dihydro-2H-thiopyran-3(4H)-one 

Downstream Products

• 5502-39-6 N-benzyl-1,3,4,5-tetrahydrothiopyrano[4,3-b]indole 
• 244-75-7 Thiopyrano<4.3-b>indol 
• 1431080-94-2 N-(4-hydroxycarbamoyl-2-methoxybenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorene 
• 1431081-02-5 N-(4-methoxycarbonyl-2-methoxybenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorene 
• 1431080-93-1 4-((3,4-dihydrothiopyrano[4,3-b]indol-5(1H)-yl)methyl)-N-hydroxybenzamide 
• 1431081-01-4 methyl 4-((3,4-dihydrothiopyrano[4,3-b]indol-5(1H)-yl)methyl)benzoate 
• 1431080-98-6 N-(4-hydroxycarbamoyl-2-methoxybenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorene-3,3-dioxide 
• 1431080-97-5 N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorene-3,3-dioxide 
• 1431081-06-9 N-(4-methoxycarbonyl-2-methoxybenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorene-3,3-dioxide 
• 1431081-05-8 N-(4-methoxycarbonylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorene-3,3-dioxide 
• 53709-62-9 4'-(4-chloro-benzenesulfonylamino)-2-(4-chloro-benzenesulfonylimino)-1-methyl-1,2,4',5'-tetrahydro-spiro[indole-3,3'-thiophene] 
• 53709-61-8 1-methyl-4'-(toluene-4-sulfonylamino)-2-(toluene-4-sulfonylimino)-1,2,4',5'-tetrahydro-spiro[indole-3,3'-thiophene] 
• 53709-50-5 4-chloro-N-(1-methyl-4',5'-dihydro-1H-spiro[indole-2,3'-thiophen]-3-ylidene)-benzenesulfonamide 
• 53709-49-2 N-(1-methyl-4',5'-dihydro-1H-spiro[indole-2,3'-thiophen]-3-ylidene)-toluene-4-sulfonamide 

Relevant articles and documents

Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition

Recent studies point towards the possible disadvantages of using hydroxamic acid-based zinc-binding groups in HDAC inhibitors due to e.g. mutagenicity issues. In this work, we elaborated on our previously developed Tubathian series, a class of highly sele

Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated

The discovery of isozyme-selective histone deacetylase (HDAC) inhibitors is critical for understanding the biological functions of individual HDACs and for validating HDACs as drug targets. The isozyme HDAC10 contributes to chemotherapy resistance and has

Thiapyran[4,3-b] indole compound and preparing method and application thereof

The invention discloses a thiapyran[4,3-b] indole compound and a preparing method and application thereof. The structure of the compound is shown in the formula 1, wherein the formula 1 is shown in the description, and R1-R5 are not all hydrogen. The compound has excellent activities of inhibiting mycelial growth, protecting detached leaves, protecting living bodies and treating the living bodiesfor rhizoctonia solani, the effects of the compound are even superior to those of positive control drugs, and the compound has an important application value in preventing and/or treating rice sheathblight.