70772-68-8 Usage
Uses
Used in Pharmaceutical Industry:
PHENYL N,N'-BIS(2-CHLOROETHYL)PHOSPHORODIAMIDATE is used as a chemical intermediate for the synthesis of anti-cancer drugs due to its alkylating properties that can disrupt DNA replication and cell division in cancer cells.
Used in Cancer Research:
In the field of cancer research, PHENYL N,N'-BIS(2-CHLOROETHYL)PHOSPHORODIAMIDATE is utilized as a model compound to study the mechanisms of action of alkylating agents and to develop new therapeutic strategies for various types of cancer.
Used in Oncology:
PHENYL N,N'-BIS(2-CHLOROETHYL)PHOSPHORODIAMIDATE is used as a chemotherapeutic agent for the treatment of certain types of cancers, including leukemia, lymphoma, and solid tumors, due to its ability to induce cell death in rapidly dividing cells.
However, it is important to note that PHENYL N,N'-BIS(2-CHLOROETHYL)PHOSPHORODIAMIDATE is highly toxic and can cause severe side effects such as nausea, vomiting, and bone marrow suppression. As a result, its use in clinical settings is carefully managed and monitored to balance its therapeutic benefits against potential risks. Ongoing research continues to explore ways to mitigate these side effects and enhance the therapeutic potential of PHENYL N,N'-BIS(2-CHLOROETHYL)PHOSPHORODIAMIDATE in the fight against cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 70772-68-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,7,7 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 70772-68:
(7*7)+(6*0)+(5*7)+(4*7)+(3*2)+(2*6)+(1*8)=138
138 % 10 = 8
So 70772-68-8 is a valid CAS Registry Number.
70772-68-8Relevant academic research and scientific papers
Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents
-
Page/Page column 6, (2008/06/13)
The present disclosure relates to salts and compositions of isophosphoramide mustard and isophosphoramide mustard analogs. In one embodiment the salts can be represented by the formula wherein A+ represents an ammonium species selected from the
Phosphorylated Nitrogen Mustards. Part 2. Anchimeric Assistance of the Fragmentation of N-(2-Chloroethyl)-2-Arylethylphosphoroamidates
Roux, Charlotte le,Modro, Agnes M.,Modro, Tomasz A.
, p. 38 - 39 (2007/10/03)
N-(2-Chloroethyl)phosphoric amido esters containing a 2-arylethyl ester function undergo thermal fragmentation to the 2-arylchloroethane, aziridine and a methaphosphate intermediate.
