70779-90-7

Basic information

• Product Name: ethyl 2-{[(1-ethoxy-4-methyl-1-oxopentan-2-yl)carbamoyl]amino}-4-methylpentanoate (non-preferred name)
• CAS NO: 70779-90-7
• Molecular Formula: C₁₇H₃₂N₂O₅
• Molecular Weight: 344.4464
• Mol File: 70779-90-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 475.6°C at 760 mmHg
• Flash Point: 241.4°C
• Density: 1.036g/cm³
• Vapor Pressure: 3.27E-09mmHg at 25°C
• Refractive Index: 1.462
• CAS DataBase Reference: ethyl 2-{[(1-ethoxy-4-methyl-1-oxopentan-2-yl)carbamoyl]amino}-4-methylpentanoate (non-preferred name)(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-{[(1-ethoxy-4-methyl-1-oxopentan-2-yl)carbamoyl]amino}-4-methylpentanoate (non-preferred name)(70779-90-7)
• EPA Substance Registry System: ethyl 2-{[(1-ethoxy-4-methyl-1-oxopentan-2-yl)carbamoyl]amino}-4-methylpentanoate (non-preferred name)(70779-90-7)

Safety Data

• Hazardous Substances Data: 70779-90-7(Hazardous Substances Data)

Upstream product

• 5070-13-3 bis-(p-nitrophenyl) carbonate 
• 2743-40-0 L-leucine ethyl ester hydrochloride 
• 64505-10-8 N-carbonyl-L-leucine ethyl ester 
• 75-44-5 phosgene 
• 2899-43-6 DL-leucine ethyl ester 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Synthesis of N,N′-carbonyl-bis-amino acids and N,N′-carbonyl-bis-peptides

A new method for the preparation of N,N′-carbonyl-bis-amino acid esters by reaction of bis(4-nitrophenyl)carbonate with amino acid esters is described. When the carbonate reacts with two equivalents of a peptide ester, N,N′-carbonyl-bis(peptide ester) is obtained but, a hydantoin derivative is formed as a side product. The hydantoin derivative is a major product, when equimolar amounts are allowed to react. Usefulness of this method for preparation of larger N,N′carbonyl-bis-peptides is demonstrated by the synthesis of the respective product from C-terminal hexapeptide of Substance P linked to the Merrifield resin.