70790-67-9

Upstream product

• 110-89-4 piperidine 
• 113526-04-8 2-(nitromethyl)-cyclohex-1-ene-3-one 
• 108-94-1 cyclohexanone 
• 927434-10-4 2-bromomethylcyclohex-2-enone 
• 105956-40-9 2-(hydroxymethyl)cyclohex-2-en-1-one 
• 107454-83-1 1-(nitromethyl)-1,2-epoxycyclohexane 

Relevant academic research and scientific papers

Transition-metal-free nucleophilic allylic substitutions of Morita–Baylis–Hillman bromides with aliphatic and aromatic amines

A simple protocol for the preparation of functionalized allylic amines under mild, transition-metal-free conditions from the reaction of Morita–Baylis–Hillman (MBH) bromides with amines is described herein. The treatment of the MBH bromides with various amines in the presence of NaI and Et3N in aqueous acetone solution and at room temperature affords the corresponding functionalized allyl amines in moderate to good yields (45–87%). The reaction is rapid and carried out at room temperature.

NEW SUBSTITUTION REACTION OF ALLYLIC NITRO COMPOUNDS. REGIOSELECTIVE REPLACEMENT OF NITRO GROUP IN CYCLIC α-(NITROALKYL)ENONES BY NUCLEOPHILES

Regioselective replacement of nitro group in cyclic α-(nitroalkyl)-enones by various nucleophiles such as stabilized carbanions, amine, NaN3, PhSO2Na and PhSNa provides the overall SN2 type products.