70797-93-2Relevant articles and documents
Pseudomonic Acid C from L-Lyxose
Keck, Garry E.,Kachensky, David F.,Enholm, Eric J.
, p. 4317 - 4325 (2007/10/02)
Full details of the total synthesis of pseudomonic acid C from L-lyxose are described.Key features of the approach involve feee-radical allylation for stereoselective C-C bond formation at C4 of lyxose, Frater alkylation to generate correct stereochemistry at C12 and C13, and stereoselective intramolecular Michael addition to establish the correct stereochemistry of the "anomeric" appendage.