708246-63-3Relevant academic research and scientific papers
An efficient, greener, and solvent-free one-pot multicomponent synthesis of 3-substituted quinazolin-4(3H)ones and thienopyrimidin-4(3H)ones
Jalani, Hitesh B.,Pandya, Amit N.,Pandya, Dhaivat H.,Sharma, Jayesh A.,Sudarsanam,Vasu, Kamala K.
, p. 4062 - 4064 (2012)
Herein, we report an efficient, greener, and solvent-free novel method for the synthesis of 3-substituted quinazolin-4(3H)ones and thienopyrimidin-4(3H) ones in a one-pot sequence using methyl anthranilate or 2-aminothiophene-3- carboxylate with N,N′-dimethyl formamide dimethyl acetal and various anilines. The driving force for this reaction is the removal of N,N′-dimethylamine by various anilines resulting in 3-substituted quinazolin-4(3H)ones and thienopyrimidin-4(3H)ones.
