708253-39-8Relevant academic research and scientific papers
CARBAMATE DERIVATIVES AND USES THEREOF
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Paragraph 01419; 01421, (2020/08/13)
The present disclosure relates to compounds of Formula (I): and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers.
TUBULIN INHIBITORS
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Page/Page column 39, (2008/06/13)
Compounds of general formula (I), (II) (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).
(4, 5, 6, 7-TETRAHYDRO-1-H-INDOL-7-YL) ACETIC ACID DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE
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Page/Page column 26, (2008/06/13)
Compounds of formula: (I); are disclosed. The compounds are useful in treating or preventing diseases associated with deposition of Aβ in the brain.
PYRAZINE-BASED TUBULIN INHIBITORS
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Page 29, (2010/02/07)
A compound of general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating a hyperproliferation-related disease state or disorder in a subject using a compound of formula (I) is also described
