708258-08-6

Usage

Uses

Used in Pharmaceutical Industry:
2-Quinolinecarboxylic acid, 6-amino-4-hydroxy-(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Environmental Regulation:
2-Quinolinecarboxylic acid, 6-amino-4-hydroxy-(9CI) is used as a subject of interest in environmental regulation due to its identification as a potential environmental pollutant. Its presence in the environment is monitored and regulated to ensure the protection of ecosystems and human health.
Used in Research and Development:
2-Quinolinecarboxylic acid, 6-amino-4-hydroxy-(9CI) is used as a research compound in various fields of chemistry and biomedicine. Its pharmacological properties, including anti-inflammatory and antioxidant effects, make it a promising candidate for further study and development of new therapeutic agents.

Upstream product

• 52144-24-8 4-hydroxy-6-nitro-quinoline-2-carboxylic acid ethyl ester 
• 52979-42-7 6-amino-4-hydroxy-2-methoxycarbonylquinoline 
• 859982-04-0 6-acetylamino-4-hydroxy-quinoline-2-carboxylic acid ethyl ester 
• 24782-43-2 ethyl 4-hydroxyquinoline-2-carboxylate 

Downstream Products

• 40107-09-3 4,5-Diamino-chinolin 
• 874497-95-7 N-(4-amino-[6]quinolyl)-acetamide 
• 56717-02-3 6-amino-quinolin-4-ol 

Relevant academic research and scientific papers

ANTIBODIES AGAINST SEROTONIN, TRYPTOPHAN AND KYNURENINE METABOLITES AND USES THEREOF

The present invention provides antibodies and methods for preparing antibodies to metabolites in the serotonin, tryptophan and kynurenine pathways, such as 5- hydroxyindole-3-acetic acid (5-HIAA), melatonin (MT) and kynurenic acid (KYNA). The specific metabolite antibodies have low cross-reactivity to structurally related metabolites, and are useful reagents for specific and sensitive immunoassays. The present invention also provides methods for using such antibodies to measure the levels of 5-HIAA, melatonin, or kynurenic acid in biological samples from human patients.

PATHWAY SPECIFIC ASSAYS FOR PREDICTING IRRITABLE BOWEL SYNDROME DIAGNOSIS

The present invention provides antibodies and methods for preparing antibodies to metabolites in the serotonin, tryptophan, kynurenine pathways. The prepared antibodies have low cross-reactivity to related metabolites, and are useful reagents for specific and sensitive immunoassays The present invention also provides stable derivatives of various metabolites and short chain fatty acids. The derivative can be conjugated to a biomolecule such as a carrier protein and combined with an adjuvant to stimulate an immune response. The derivatives can also be conjugated to other biomolecules.

2-AMINOCARBONYL-QUINOLINE COMPOUNDS AS PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS

Compounds of formula (I), where m, n, R1, R2, R3, R4 and R6 are described herein, are useful as inhibitors of platelet adenosine diphosphate. Pharmaceutical compositions containing these compounds, methods of using these compounds as antithrombotic agents and processes for synthesizing these compounds are also described herein.

Platelet adenosine diphosphate receptor antagonists

Compounds of the following formula (I): where a, b, R1, R2, R4 and R6 are described herein, are useful as inhibitors of platelet adenosine diphosphate. Pharmaceutical compositions containing these compounds, met