Cas 708274-30-0,Cyclohexanone, 4-hydroxy-4-(3-pyridazinyl)-

708274-30-0

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Basic information

Product Name: Cyclohexanone, 4-hydroxy-4-(3-pyridazinyl)-
Synonyms:
CAS NO:708274-30-0
Molecular Formula: C10H12N2O2
Molecular Weight: 192.217
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Cyclohexanone, 4-hydroxy-4-(3-pyridazinyl)-(CAS DataBase Reference)
NIST Chemistry Reference: Cyclohexanone, 4-hydroxy-4-(3-pyridazinyl)-(708274-30-0)
EPA Substance Registry System: Cyclohexanone, 4-hydroxy-4-(3-pyridazinyl)-(708274-30-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 708274-30-0(Hazardous Substances Data)

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708274-30-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 708274-30-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,8,2,7 and 4 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 708274-30:
(8*7)+(7*0)+(6*8)+(5*2)+(4*7)+(3*4)+(2*3)+(1*0)=160
160 % 10 = 0
So 708274-30-0 is a valid CAS Registry Number.

708274-30-0Upstream product

708274-30-0Downstream Products

1290546-23-4 N-(2-((R)-1-(trans-4-hydroxy-4-(pyridazin-3-yl)cyclohexyl)pyrrolidin-3-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide

708274-30-0Relevant academic research and scientific papers

A METHOD OF TREATING LIVER FIBROSIS

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, (2012/09/11)

The present invention relates to a method of treating hepatis C and/or liver fibroisis with 3-cycloalkylaminopyrrolidine derivatives of the present invention

Discovery of INCB3284, a potent, selective, and orally bioavailable hCCR2 antagonist

Xue, Chu-Biao,Feng, Hao,Cao, Ganfeng,Huang, Taisheng,Glenn, Joseph,Anand, Rajan,Meloni, David,Zhang, Ke,Kong, Lingquan,Wang, Anlai,Zhang, Yingxin,Zheng, Changsheng,Xia, Michael,Chen, Lihua,Tanaka, Hiroyuki,Han, Qi,Robinson,Modi, Dilip,Storace, Lou,Shao, Lixin,Sharief, Vaqar,Li, Mei,Galya, Laurine G.,Covington, Maryanne,Scherle, Peggy,Diamond, Sharon,Emm, Tom,Yeleswaram, Swamy,Contel, Nancy,Vaddi, Kris,Newton, Robert,Hollis, Greg,Friedman, Steven,Metcalf, Brian

, p. 450 - 454 (2011/08/22)

We report the identification of 13 (INCB3284) as a potent human CCR2 (hCCR2) antagonist. INCB3284 exhibited an IC50 of 3.7 nM in antagonism of monocyte chemoattractant protein-1 binding to hCCR2, an IC 50 of 4.7 nM in antagonism of c

3-Cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors

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Page/Page column 29, (2008/06/13)

The present invention relates to 3-cycloalkylaminopyrrolidine derivatives of the formula I: (wherein R1, R2, R3, R4, R5, R6, R7, X, Y and Z are as defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of chemokine receptors and more specifically as modulators of the CCR2 and/or CCR5 receptor. The compounds and compositions of the invention may bind to chemokine receptors, e.g., the CCR2 and/or CCR5 chemokine receptors, and are useful for treating diseases associated with chemokine, e.g., CCR2 and/or CCR5, activity, such as atherosclerosis, restenosis, lupus, organ transplant rejection and rheumatoid arthritis.

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