70841-85-9 Usage
Uses
Used in Organic Synthesis:
α,α-dihydroxyl diisopropyl malonate is used as a reagent for the synthesis of unsymmetrical secondary amines. It acts as a singly N-electrophilic reagent towards strong C-nucleophiles such as alkyland arylmetals (e.g., Grignard reagents), enabling the preparation of these amines at low temperatures and in the absence of transition metal catalysts.
Used in Pharmaceutical Industry:
α,α-dihydroxyl diisopropyl malonate is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly in the development of new drugs and drug candidates.
Used in Chemical Research:
α,α-dihydroxyl diisopropyl malonate is used as a research tool in academic and industrial laboratories to study the reactivity and properties of N-umpolung reagents and their applications in organic synthesis and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 70841-85-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,8,4 and 1 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 70841-85:
(7*7)+(6*0)+(5*8)+(4*4)+(3*1)+(2*8)+(1*5)=129
129 % 10 = 9
So 70841-85-9 is a valid CAS Registry Number.
70841-85-9Relevant academic research and scientific papers
Facile synthesis of 1,2,3-tricarbonyls from 1,3-dicarbonyls mediated by cerium(IV) ammonium nitrate
Sivan, Akhil,Deepthi, Ani
supporting information, p. 1890 - 1893 (2014/03/21)
A mild and efficient protocol for the synthesis of vicinal tricarbonyl compounds from β-dicarbonyls in a single step using cerium(IV) ammonium nitrate as a catalytic oxidant is described. Ease of execution, wide substrate scope and the suitability for the synthesis of commercially important compounds like ninhydrin, alloxan and oxoline make this reaction particularly noteworthy.
