70855-59-3 Usage
Description
1H-Inden-5-ol,2,3-dihydro-3,6-dimethyl-1-(2-methyl-1-propenyl)-,(1R,3S)-rel-(+)is a chiral chemical compound with the molecular formula C15H22O. It features an indene ring system, a hydroxyl group, and a methyl-1-propenyl side chain. 1H-Inden-5-ol,2,3-dihydro-3,6-dimethyl-1(2-methyl-1-propenyl)-,(1R,3S)-rel-(+)'s specific stereochemistry is indicated by the (1R,3S)-rel-(+)designation, which is crucial for its potential applications.
Uses
Used in Pharmaceutical Applications:
1H-Inden-5-ol,2,3-dihydro-3,6-dimethyl-1-(2-methyl-1-propenyl)-,(1R,3S)-rel-(+)is used as a building block in pharmaceutical applications due to its unique structure and stereochemistry. Its dihydro-indenol framework and chiral centers make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 1H-Inden-5-ol,2,3-dihydro-3,6-dimethyl-1-(2-methyl-1-propenyl)-,(1R,3S)-rel-(+)serves as a valuable intermediate for the synthesis of more complex organic molecules. Its specific stereochemistry and functional groups can be utilized in various synthetic routes to create a wide range of compounds.
Used in Fragrance and Flavor Formulations:
Due to its unique structure and stereochemistry, 1H-Inden-5-ol,2,3-dihydro-3,6-dimethyl-1-(2-methyl-1-propenyl)-,(1R,3S)-rel-(+)may have potential applications in the fragrance and flavor industry. Its chiral nature could contribute to distinct olfactory and gustatory properties, making it a candidate for the development of novel scents and tastes.
Used in Chiral Chemical Research:
The specific stereochemistry of 1H-Inden-5-ol,2,3-dihydro-3,6-dimethyl-1-(2-methyl-1-propenyl)-,(1R,3S)-rel-(+)makes it an interesting subject for research in the field of chiral chemistry. Studying its properties and interactions can provide insights into the role of stereochemistry in chemical reactions and the development of enantioselective processes.
Check Digit Verification of cas no
The CAS Registry Mumber 70855-59-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,8,5 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 70855-59:
(7*7)+(6*0)+(5*8)+(4*5)+(3*5)+(2*5)+(1*9)=143
143 % 10 = 3
So 70855-59-3 is a valid CAS Registry Number.
70855-59-3Relevant articles and documents
Asymmetric Hydroarylation of Enones via Nickel-Catalyzed 5- Endo-Trig Cyclization
Qin, Xurong,Yao Lee, Marcus Wen,Zhou, Jianrong Steve
supporting information, p. 5990 - 5994 (2019/08/20)
A nickel-catalyzed reductive cyclization of enones affords a wide array of indanones in high enantiomeric induction. The reaction is featured with an unprecedented broad scope of substrates. The versatility of the new method is demonstrated in several short stereoselective syntheses of medically valuable (R)-tolterodine, parent and deuterated (+)-indatraline, and an antitumor natural product, (+)-multisianthol. In comparison, these compounds cannot be prepared satisfactorily via analogous processes catalyzed by palladium.
(+)- And (-)-mutisianthol: First total synthesis, absolute configuration, and antitumor activity
Bianco, Graziela G.,Ferraz, Helena M. C.,Costas, Arinice M.,Costa-Lotufo, Leticia V.,Pessoa, Claudia,De Moraes, Manoel O.,Schreins, Marcus G.,Pfaltz, Andreas,Silva Jr., Luiz F.
experimental part, p. 2561 - 2566 (2009/09/25)
The first synthesis of the natural product (+)-mutisianthol was accomplished in 11 steps and in 21% overall yield from 2-methylanisole. The synthesis of its enantiomer was also performed in a similar overall yield. The absolute configuration of the sesquiterpene (+)-mutisianthol was assigned as (15,37?). Key steps in the route are the asymmetric hydrogenation of a nonfunctionalized olefin using chiral iridium catalysts and the ring contraction of 1,2-dihydronaphthalenes using thallium(III) or iodine(III). The target molecules show moderate activity against the human tumor cell lines SF-295, HCT-8, and MDA-MB-435.
