7087-36-7

Usage

InChI:InChI=1/C10H18/c1-9(2)10-7-5-3-4-6-8-10/h3-8H2,1-2H3

Upstream product

• 56881-85-7 (dibromomethylene)cycloheptane 
• 917-54-4 methyllithium 
• 16642-56-1 2-(1-cycloheptenyl)-2,2-dimethylacetic acid 
• 67-64-1 acetone 
• 502-42-1 cycloheptanone 
• 57233-33-7 1-isopropylcycloheptanemethanol 
• 60433-00-3 methyl cycloheptanecarboxylate 
• 851537-47-8 4-(1-isopropyl-cycloheptanecarbonyl)-benzoic acid 
• 851537-44-5 1-isopropylcycloheptyl 4-cyanophenyl ketone 
• 851537-38-7 (4-fluoro-phenyl)-(1-isopropyl-cycloheptyl)-methanol 
• 851537-41-2 1-isopropylcycloheptyl 4-fluorophenyl ketone 
• 851537-50-3 4-(1-isopropyl-cycloheptanecarbonyl)-benzoic acid methyl ester 
• 920-39-8 isopropylmagnesium bromide 
• 17257-36-2 1-Isopropylcycloheptene 

Downstream Products

• 75600-30-5 1-Methylcycloheptylmethylketon 
• 75600-22-5 N-[2,2-Dimethyl-cyclooct-(E)-ylidene]-benzenesulfonamide 
• 75600-32-7 1-Methylcyclooctylmethylketon 
• 75600-23-6 N-[2,2-Dimethyl-cyclonon-(E)-ylidene]-benzenesulfonamide 

Relevant academic research and scientific papers

Photochemistry of 1-isopropylcycloalkyl aryl ketones: Ring size effects, medium effects, and asymmetric induction

(Chemical Equation Presented) The n = 0, 1, and 2 ketones shown above undergo Yang photocyclization in solution, but only the n = 1 analogues react this way in the solid state. Based on X-ray crystallography, these differences in reactivity are attributed to an unusually large distance for 1,4-hydroxybiradical cyclization in the solid state for the n = 0 and 2 ring systems, which leads to predominant reverse hydrogen transfer (rht). Enantiomeric excesses of up to 99% can be achieved in the case of the n = 1 system through the use of the solid-state ionic chiral auxiliary method of asymmetric synthesis.

Regioselective radical cyclization initiated by the reaction of allylic hydroperoxides with iron(II) sulfate

Treatment of 1-methyl-2-methylene-1-cyclohexyl hydroperoxide with a mixture of FeSO4/CuCl2 yielded 1-(1-chlorocyclohexyl)ethanone as the major product consistent with 6-endo-trig cyclization of the intermediate 5-acetylhex-5-enyl rad

A Convenient Reagent for the Intermolecular Coupling of Aldehydes and Ketones to Form Olefins

When aldehydes or ketones are treated with titanium tetrachloride and amalgamated magnesium turnings in tetrahydrofuran at 0 deg C for 2 h and subsequently under reflux for 24 h, reductive coupling occurs to give olefin in high yield.The optimum ratio of carbonyl substrate to titanium reagent was found to be 1 : 4.Examples of symmetrical and mixed couplings are given.Intramolecular coupling was not successful.

Cyclizations of ω-Allenyl Radicals

Allenyl halides of structure (CH3)2C=C=CH(CH2)nX with n=3-6 have been prepared and reacted with n-Bu3SnH to generate the corresponding radicals for examination of the cyclization reactions of these reactive intermediates.The observed hydrocarbon products indicate that cyclization occurs for the n=3,4, and 5 radicals but not for the n=6 species.The n=3 radical isomerizes very efficiently by intramolecular addition to the sp carbon of the allene group.The n=5 intermediate reacts relatively slowly by attack at the near sp2 carbon.Both cyclization modes are observed for the n=4 species.The details of these radical cyclizations are discussed.