708995-56-6

Basic information

• Product Name: 3-benzyl-6-(4-bromophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• Synonyms: 3-benzyl-6-(4-bromophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• CAS NO: 708995-56-6
• Molecular Formula: C₁₆H₁₁BrN₄S
• Molecular Weight: 371.25434
• Mol File: 708995-56-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-benzyl-6-(4-bromophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-6-(4-bromophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(708995-56-6)
• EPA Substance Registry System: 3-benzyl-6-(4-bromophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(708995-56-6)

Safety Data

• Hazardous Substances Data: 708995-56-6(Hazardous Substances Data)

Upstream product

• 937-39-3 2-phenylacetylhydrazine 
• 101-97-3 Ethyl 2-phenylethanoate 
• 87239-94-9 potassium-3-(phenylacetyl)dithiocarbazate 
• 586-76-5 4-Bromobenzoic acid 
• 13373-10-9 5-Benzyl-4-amino-3-mercapto-1,2,4-triazole 

Relevant articles and documents

Studies on fused heterocyclic 3,6-disubstituted-1,2, 4-triazolo-1,3,4- thiadiazoles: Synthesis and biological evaluation

In this study, a series of 3,6-disubstituted-1,2, 4-triazolo-[3,4-b]-1,3,4- thiadiazoles (5a-t) were synthesized by condensing 4-amino-3-mercapto-(4H)-1,2, 4-triazoles (4a-c) with different aromatic or aroyl acids through one-pot reaction. The compounds were evaluated for their anti-inflammatory, analgesic, ulcerogenic, and lipid peroxidation actions. Some of the newly synthesized compounds showed very good anti-inflammatory activity with low GI toxicity and reduced lipid peroxidation. These compounds also showed interesting profile of analgesic activity in acetic acid-induced writhing test. The findings of the study indicate that the synthesized compounds have superior GI safety profile along with reduction in lipid peroxidation as compared to that of the standard. Springer Science+Business Media, LLC 2010.